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Drugs & Clinical Trials
September 30, 2012

Bath Salts – Designer Drug Danger

By Harry L Leider, MD, MBA | 5 Comments | Share | Print | Email | Tweet | Like | 1+
Bath salts

The media has been abuzz in recent weeks about “bath salts” — but they’re not writing headlines about the scented crystals used for bathing or Epsom salts. Bath salts are the latest designer street drug to raise alarm bells across Europe and the United States. Marketed falsely under benign-sounding names that also include “research chemicals” or “plant food,” these substances are part of a dangerous new class of drugs called synthetic cathinones.

Synthetic cathinones are structurally and pharmacologically similar to methamphetamine, Ecstasy, and LSD, which are also considered designer drugs — that is, manufactured versions of controlled substances. Synthetic cathinones pose serious health risks and danger to the public. Side effects include chest pains, increased blood pressure, increased heart rate, agitation, hallucinations, extreme paranoia, and delusions. They are addictive and have been linked to deaths. A number of incidents of bizarre behavior have fueled recent media stories.

But what makes them particularly dangerous is their ease of access — bath salts are available legally via the internet or in drug paraphernalia stores. That’s because the so-called “chemists” who produce them make constant, minor alternations to the drugs’ chemical make-up, dodging Drug Enforcement Administration (DEA) Schedule 1 classification on a technicality — and leading many to claim the drugs provide a “legal high.” Further fueling their popularity, the outlets that sell bath salts often promise that urine drug screens will not detect their presence. Not so…

Ameritox, a uring drug testing company, announced recently the launch of a test for bath salts that not only detects three common synthetic cathinones that the DEA has categorized as controlled substances, but also tests for five other chemical components used commonly in bath salts products.

The battle to keep up with the latest formulations of these designer drugs is truly a game of “cat and mouse.” The DEA placed three specific synthetic cathinones into its Schedule 1 category of controlled substances in October 2011, citing the move as “necessary to avoid imminent hazard to the public safety” due to high abuse potential and lack of medical use.

But there are likely dozens of synthetic cathinones on the street today.

The public safety solution requires effort at multiple levels — with physicians, scientists, communities, law enforcement, and policy makers each playing a collaborative role. As the DEA works tirelessly to categorize these substances, other players are bringing their scientific expertise to bear on the problem.

Specialty laboratories work hard to stay ahead of the game in anticipating new formulations and launching new tests to detect these dangerous substances – and joining forces with the DEA, the physicians conducting these tests, and insurance companies could make our progress even stronger:

  • Physicians need to be educated to identify patients suffering from the side effects of bath salts and be able to report increased use in their community. Using techniques like urine drug testing can help.
  • Insurance companies need to be encouraged to cover drug screenings, so that data about drug use trends can be provided to the DEA and physicians to help reduce their use.
  • The public needs to be educated about this dangerous and unregulated category of drugs, in particular that just because drugs are sometimes legal doesn’t mean they are safe.
  • The DEA needs a faster way to outlaw these drugs by class, rather than by substance.

By working together, we can help reduce the threat of “bath salts” to individual’s health and to enhance public safety.

References

Rosenbaum CD, Carreiro SP, & Babu KM (2012). Here today, gone tomorrow…and back again? A review of herbal marijuana alternatives (K2, Spice), synthetic cathinones (bath salts), kratom, Salvia divinorum, methoxetamine, and piperazines. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 8 (1), 15-32 PMID: 22271566

Prosser JM, & Nelson LS (2012). The toxicology of bath salts: a review of synthetic cathinones. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 8 (1), 33-42 PMID: 22108839

U.S. Department of Justice: Drug Enforcement Agency. Federal Register / Vol. 76, No. 204 / Friday, October 21, 2011 / Rules and Regulations.

European Monitoring Centre for Drugs and Drug Addiction. EMCDDA–Europol 2011 Annual Report on the implementation of Council Decision 2005/387/JHA. April 2012.

Image via yonibunga / Shutterstock.

Harry L Leider, MD, MBA

Harry Leider, MD, MBA, FACPE, has a broad range of experience in clinical medicine and research, disease management and managed care. He leads a variety of progressive initiatives at Ameritox, including directing the company’s clinical research projects, working with national experts in the area of chronic pain designing programs and tools that support practicing physicians, and designing and implementing programs that help payers improve quality of care for patients with chronic pain. Dr. Leider is board-certified in Internal Medicine and Medical Management.

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5 Responses

  1. antianticamper says:
    September 30, 2012 at 7:08 am

    “The DEA needs a faster way to outlaw these drugs by class, rather than by substance.”

    Do you think the War on Drugs has, overall, been a success from a cost-benefit perspective? (I don’t.)

    Do you think a worldwide army of amatuer chemists in competition with rapidly changing laws makes the conventional legal battle MORE or LESS winnable? (I think “less”.)

    Do you think there is a better, more sophisticated, more practical approach to the problems associated with the universal (in time and culture) human desire to alter consciousness? (I do.)

    Reply
  2. Richard Kensinger, MSW says:
    September 30, 2012 at 10:59 am

    Bath Salts, also known as MDVP joins a growing list of “designer” drugs. In my area, use is now slightly declining due to its illegal status in PA. It produces most bizarre psychotic experiences inc. marked aggression & violence. Its acts both as a potent psychotic & as a potent stimulant. We’ve experienced about a dozen deaths in Central PA.

    The US of A is # 1 in making, selling & taking psychoactive agents! This is a most dubious distinction.

    Rich

    Reply
    • Jeff says:
      March 31, 2013 at 7:29 pm

      Hey I’m not sure what u meant by the USA being the #1 manufacturer of phycoactive drugs. What are you regarding? I hope I don’t sound rude I’m just curious because this is about bath salts, and somewhere (don’t feel like looking it up) in Malaysia is the #1 producer of bath salts specifically. I was just wondering if you could give me an idea of what of what your referring to because I’m an addict on bath salts for 3 years and I’d appreciate some new information, because as of the past year when everyone started talking about bath salts, I’ve been around linger and know EXCACTLY what I’m talking about and then some when it comes to bath salts. Like I said sorry if I sounded rude im not questioning your knowledge. Just what do u mean like I’m pretty sure its not bath salts. It would be ALOT more expensive than 17-32.6 dollars if it was manufactured in the USA. Just let me know, with an example please. Like pentylone or methyl one, some research chemicals or whatever your talking about.

      Reply
    • Anonymous says:
      April 1, 2013 at 5:53 pm

      Jeff & others,

      Indeed, when we consider all psychoactive agents, inc. “bath salts” we are # 1. Just for instance, consider that we use almost 85% of the psychostimulants, such as Ritalin & Adderall & the like. i am a professor of psychology, & my references are numerous & pulled from the clinical literature.

      i take no offense to your point, & thank you for the opportunity to clarify my point!

      Rich

      Reply
  3. phenotype_i says:
    October 9, 2012 at 1:30 pm

    Synthetic cathinones are structurally and pharmacologically similar to methamphetamine, Ecstasy, and LSD

    And Dopamine and Adrenaline!!! By that dubiously slanted comparison. These cathinones are mostly like Meth (related to Adderal, and Ritalin, prescribed by “M.D.s” as widely as 1/3 US population). Idiots be ware. Physicians: Heal Thine Selves.

    Reply

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