Hi Dirk,
A very thoughtful article. I wonder if it might not be useful to go back to Andrews and Thomson and ask them to comment on depression when it becomes severe mental illness (SMI) and ask them to fit that into their scheme of things.

I think its the byproduct of the over-functional brain. Our irrational emotional dictates simply don’t make rational sense. It’s not some coping mechanism at all. This mechanism has the ability to wipe memory cells, and I don’t think that is advantageous in any way. It’s simply our intelligence that says that we’re not the center of the universe clashing with our survivalist emotions that says we and our ways are universally important

As I read this, I was reminded of the effects recently noted in some journals regarding how epigenetic markers affect gene expression. Experiments with mice show that the introduction of certain methyl groups into their diets can produce behavioral changes. Gene therapy experiments show their effects on the production and use of neuropeptides. And the connection between diet and depression is well-known.

So I am left wondering, could the presence of certain methyl groups in the diet lead causally to depression?

Depression, stress and their complications:

This disease is known as burned black bile. As it was said, black bile is one of the four humors of human body which will bring complications if one of them dominates other others.
According to the age, gender, physical power and temperament of individuals, these complications differs and are demonstrated in various forms.
If the dominance of black bile continues for a long time, it will changes into concentrated black bile or termed as burned black bile. No one usually considers this dominance at the onset of the disease which causes the treatment of the disease to be extended.

Causes of Disease: The most common causes of this disease are as follows:
Consuming some of the edibles in specific mental states
If one eats very sour edibles or lentil in a disturbed mental state such as severe anger, fear, even intense happiness, the body secretes much black bile and pickles and lentil increases this secretion the result of which is the dominance of the black bile over the other ones which causes complications such as phobia, anger, hallucination, sadness, etc…
From among the other causes are hereditary black bile humor and being in inappropriate mental state for a long time.

Common Symptoms:

Initial stages: Indifference, impatience, disgust, inability to enjoy, hopelessness, feebleness, fatigue, social reclusion, anorexia, gluttony, constipation, losing sexual desire, having problem in taking decision.

Severe stages: spontaneous weeping without any specific reason, irritability, thinking of suicide, various pains without any symptom, tongue split, urticaria, and gastric acid reflex.

Considerations: Any of the abovementioned symptoms may appear individually or collectively.

Disease intensifying factors: Anger, having an obsessive, orderly and serious, idealistic or highly dependent personality, family background in depression, addicted to alcohol, failure in business, unsuccessful marriage, disputes with others, death or loss of one of the dear relatives or friends, changing occupation or moving into a new place, etc.

Medication(Treatment)

In modern medicine, there is no significant treatment for this disease because its cause has not been diagnosed yet. But in traditional medicine, its factor has been known; therefore it is easily cured.

Treatment Procedure:

1. Avoid any kind of sour edible and lentil
2. Consume little salt
3. Provide a calm and convenient situation
4. Avoid loneliness and reclusion
5. Wear light-color clothes
6. Leave home and go to nature once a week to use its healthy weather

Herbal Medicines:

1. Borage: This plant has been known as the tranquilizer since the ancient times and can help curing the abovementioned disease because of its anti-excitement property.
2. Syrup of currants extract (black bile syrup): This herbal medicine cures all the mental diseases such as depression, hallucination, irrational sadness, stress, irrational worries and insomnia.

Considering the ingredients extracted from plants, black bile syrup is a strong melting agent black bile and regulator of black bile secretion; therefore, daily consumption of this herbal medicine and completing its treatment cycle results in full and absolute treatment of depression and its resulted complications.