Late 1980s I was under massive stress, blackmail froma hospital (investor) and lack of funds due from hospital (I operated an HMO). I had two heart attacks but no permanent muscle damage (doctors were confused). This all was followed by tremendous anxiety attacks. My physician told me to stay in the area and die, or leave and possibly live. Stress was so great that I was unable to function in any capacity. Since leaving the position I have had several more heart attacks and 2 strokes. “No noticable damage”. The anxiety attacks have stopped. However, massive hive attacks began in the late 1980s and continue to this day. I take aterak at night and fexofenadrine in the mornings supplementated by xanax. I was sent to a dermatolgist and his analysis came back ‘idiopathic’. Perhaps I should have seen a neorologist for I firmly believe the hives are being generated from the brain. Your link to more explanations on the brain aspect does not work. I would like to learn more about the specifics of the brain function, of the loss of nuerons, syanaptic or dendrite problems, white matter, or more. No local physicians seem to know anything about the participation of the brain in these hive attacks, some so major that I end up in the ER, whole body hives. The scars stay for days. I am informed via pin prick like sensations that give prior warning of an attack. Sometimes I will take several aterak, fexofenadrine and xanax tablets. If I can fall asleep for several hours I sometimes improve significantly. This has gone on for 20 years and I am only now, through my own research, determining the the brain my be the catalyst for this problem. Therefore I am looking for information that can more readily explain the mind’s function in this regard. Perhaps armed with such information I can feret our some physician that can understand the reactions. I am getting tired of the ‘idoiopathic’ response. Some physicians make a joke of it when using that nonsensical work. Any information resource will be appreciated.