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Monthly Archive for June, 2009

Tree with light adam

Opinion

Time for a Change – Gender Reassignment

June 21, 2009 | By T. A. McNamee, MD | 9 Comments

I still remember him plainly: middle-aged, married, paunchy around the middle. He didn’t come in to the clinic because he was sick or had a chronic medical illness. He came in because he wanted to be a woman.Gender reassignment was not something I had learned about in medical school. It was mentioned in passing, but there were no lectures about how to correctly dose estrogen for the male-to-female transsexual. I frankly had no idea what to do. I think my surprise and confusion were apparent, as the man blushed a little and suggested that I might want to refer him to a specialist.

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Psychology & Psychiatry

Common Treatment Ineffective for Autism

June 18, 2009 | By Jennifer Gibson, PharmD | 3 Comments

The growing prevalence of autism worldwide has parents and clinicians searching for effective treatment options. Though not approved by the United States Food and Drug Administration for the treatment of autism, a common class of antidepressants is often prescribed to treat the symptoms of autism in children. The selective serotonin reuptake inhibitors (SSRIs) are among the most widely used drugs for autism treatment, even though the effectiveness to date has been questionable. A new study published in the June issue of Archives of General Psychiatry reports that, not only are SSRIs ineffective, they may actually cause unintended side effects.

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Drugs & Clinical Trials

Marijuana Withdrawal Syndrome

June 15, 2009 | By Dirk Hanson, MA | 284 Comments

There are now several clinical trials showing that mice and dogs show evidence of cannabis withdrawal. (For THC-addicted dogs, it is the abnormal number of wet-dog shakes that give them away.) Today, scientists have a much better picture of the jobs performed by anandamide, the body’s own form of THC. This knowledge helps explain a wide range of THC withdrawal symptoms.

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Drugs & Clinical Trials

NSAIDs – Prevention or Just Delay of Dementia?

June 12, 2009 | By Jennifer Gibson, PharmD | 1 Comment

Many epidemiological and observational studies have reported that the use of nonsteroidal anti-inflammatory drugs (NSAIDs) reduces the risk of developing dementia and Alzheimer’s disease (AD) in the elderly. To date, there have been no clinical trials to support these claims, and there are just as many studies that report conflicting results. In a recent issue of Neurology, study authors reported that heavy NSAID use was actually associated with an increased risk for dementia.

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