BioPsychoSocial Health | By March 28, 2006 | By Shaheen E Lakhan, MS, MEd, PhDcloseShaheen E Lakhan, MS, MEd, PhD Name: Shaheen Lakhan
Site: http://slakhan.gnif.org
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About: Dr. Lakhan is the Executive Director of the Global Neuroscience Initiative Foundation (GNIF). He administers a host of projects in bioethics, biotechnology, emergency management, global philanthropy, proteomics, and psychiatry -- to name a few disciplines. | 0 Comments

Vulnerability-Stress-Coping Model for Schizophrenia

Schizophrenia is a multifaceted disorder that manifests by both genetic and environmental factors. A plethora of twin and adoption studies suggest major genetic influences on the pathogenesis of schizophrenia; however, a MZ concordance of 50% also suggests environmental factors (Cardno et al., 1999). [Note, a concordance of 100%, or absolute probability that both "identical" twins are afflicted or not, would suggest a single gene disorder, as in sickle cell anemia and cystic fibrosis.] These family studies reveal that schizophrenia is a complex genetic disorder, akin to diabetes and most cancers, where not but multiple causative genes contribute to susceptibility — a polygenetic disease. Moreover, there are presumably environmental factors that contribute to the onset. Read more →