Articles Tagged ‘stressful life events’
Psychiatry & Psychology | By June 04, 2008 | By Lindsey Kay, MD | 2 Comments
Interactive Effects of Genetics on Depression
It is well known that depression results from the combination of many different factors. Environmental effects, such as stressful life events, are a trigger in many patients for the development of major depressive disorder (MDD) and the milder disorder, dysthymia. It is also true that the same major stressors will not produce depressive symptoms in some, pointing to underlying risk factors that make some more susceptible to depression than others. Researchers have attempted to identify a single gene that can be linked to MDD, and while familial clustering of depressive disorders is a common finding, single-gene inheritance patterns are not seen. Instead, patterns suggested that several genes are involved in depression, and a recent research study demonstrated the interactive effects of these genes on the disease. Read more →
- Vulnerability-Stress-Coping Model for Schizophrenia
Schizophrenia is a multifaceted disorder that manifests by both genetic and environmental factors. A plethora of twin and adoption studies suggest major genetic influences on the pathogenesis of schizophrenia; however, a MZ concordance of 50% also suggests environmental factors (Cardno et al., 1999). [Note, a concordance of 100%, or absolute probability that both "identical" twins are afflicted or not, would suggest a single gene disorder, as in sickle cell anemia and cystic fibrosis.] These family studies reveal that schizophrenia is a complex genetic disorder, akin to diabetes and most cancers, where not but multiple causative genes contribute to susceptibility — a polygenetic disease. Moreover, there are presumably environmental factors that contribute to the onset. Read more →
Sunday, March 21, 2010
- Religion - A "Natural" Phenomenon?
- Psychotropics and Youth, Part 1 - The Five Myths
- How Culture Shapes Our Mind and Brain
- Sex, Violence and The Male Warrior Hypothesis
- The Secret to Good Health – Listen to the Data
- If Herbal Medicine is Medicine, Shouldn't it be Treated as Such?
- Neurology, Neurosurgery, and Neuroscience Conferences for 2010
- Too Much Information?
- "I Feel Your Pain" - The Neural Basis of Empathy
- Income Inequality and Health Outcomes
- The Evolution of Depression
- Journal Retracts Autism Research
- Speaking in Tongues - A Neural Snapshot
- Post-Partum Psychosis - Rare but Real
- Is Your Doctor Happy or Burnt-Out?
- Ginkgo Biloba Ineffective... Again
- Worried Well on the Web
- Psychotropics and Youth, Part 2 - The Solutions
- Why Some Human Brains Become Leaders, While Others Followers?
- Postoperative Cognitive Dysfunction
- Let the Matches Begin!
- My Nephew and his Brain, Part 4 – Their Life Today
- My Nephew and his Brain, Part 3 – Try to Work Out their Troubles
- My Nephew and his Brain, Part 2 – Revealed to be Complicated
- My Nephew and his Brain, Part 1 – Introduction
- Deep Brain Stimulation – A New Frontier in Psychiatry
- Psychotropics and Youth, Part 3 – Equip Teachers with Prescription Pads?
- Why Some Human Brains Become Leaders, While Others Followers?
- Brain Blogger Finalist for Two 2010 Research Blogging Awards in Neuroscience and Psychology
- Tall Tales of Diabetic Amputations
- Psychotropics and Youth, Part 2 – The Solutions
- Brain Blogging, Forty-Ninth Edition
- How Your Brain Groups Words
- The Child Brain and the Playing Teacher
- You Have a Right to Choose if we Agree
- Measuring Quality in Primary Care
- Matchmaker, Matchmaker Make Me A Match – The NRMP Main Residency Match
- Psychotropics and Youth, Part 1 – The Five Myths
- When It Comes to Aging, Size Matters
- “I Feel Your Pain” – The Neural Basis of Empathy
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