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Drugs & Clinical Trials Topic

Looking glass

Into the Looking Glass – Stroke, tPA, and Avoiding a Fate Worse Than Death

November 4, 2012 | By John Galbraith Simmons | 5 Comments

Stroke, a major cause of death and the leading cause of adult disability, can leave victims unable to walk, talk, eat or take care of themselves. To treat stroke while it’s happening, the "clot-busting" drug tPA (tissue plasminogen activator) has been proven to save brains from damage and reduce or even completely avoid disability. Patients require a CAT-scan to assure diagnosis and the drug must be administered within 4.5 hours after onset of symptoms. In today’s medical environment, that shouldn't be an overwhelming obstacle.

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Botox to face

Depressed About Wrinkles? BOTOX Can Help

November 1, 2012 | By Amy Wong, MS | 15 Comments

The signs of aging can never seem to escape us: your eyes get puffier, your wrinkles lines extend in length, and the creases at the corners of your mouth deepen substantially. Soon, you remember a friend’s nonchalant remark that you seem to look angry all the time…even when you’re smiling.  Perhaps you are angry, both angry and sad that your youthful vigilance has come and gone all too quickly. Thankfully, there may be one treatment available that can offer a boost to your spirits: a recent study published in the Journal of Psychiatric Research reported that single treatment of age lines with botulinium toxin A (BTX-A or BOTOX) may alleviate depressive symptoms in patients who do not improve sufficiently on previous medication.

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Grey smoke over black background

Smoking and Adolescent Brain Development

October 14, 2012 | By Shefali Sabharanjak, PhD | 8 Comments

When it comes to substance abuse like smoking or abuse of intoxicating drugs, it is very difficult to determine what a "safe" limit of exposure is.  Quite often, the initial exposure to mood altering substances like nicotine occurs during the teenage years. The period of adolescence is marked by a tendency towards risk-taking behavior which often results in ‘experimental’ exposure to psychedelic substances. Adolescents who tend to flirt with danger in this fashion are often convinced that a small trial will not actually have lasting damaging effects. However, research on the development of prefrontal cortex in similarly age-matched animals says otherwise.

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Bath salts

Bath Salts – Designer Drug Danger

September 30, 2012 | By Harry L Leider, MD, MBA | 5 Comments

The media has been abuzz in recent weeks about "bath salts" -- but they’re not writing headlines about the scented crystals used for bathing or Epsom salts. Bath salts are the latest designer street drug to raise alarm bells across Europe and the United States. Marketed falsely under benign-sounding names that also include "research chemicals" or "plant food," these substances are part of a dangerous new class of drugs called synthetic cathinones.

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