Drugs & Clinical Trials Category
Drugs & Clinical Trials | By October 14, 2008 | By Jennifer Gibson, PharmD | 1 Comment
Hope for Huntington’s Disease – Xenazine for Chorea
Huntington’s Disease (HD) is a fatal, inherited neurodegenerative disease. It affects approximately 30,000 people in the United States, with another 200,000 at risk of developing the disease. There is currently no cure.
Hope is on the horizon, however, with the FDA’s approval of the first drug to treat HD in August of 2008. The drug, Xenazine (tetrabenazine) was developed in the 1950’s to treat psychosis, but had limited success. Now, it is available in the United States, as well as Europe, Canada, and Australia, to treat one of the hallmark symptoms of HD — chorea. Read more →
- Life in a Bubble – The Dangers of Triclosan
- New Treatment for Alzheimer’s Disease?
- Public Health Needs a Shot in the Arm
- Anti-Epileptic Drugs and the Risk of Suicide
- Pharmacists Really Do Have Prescribing Power
- Prescriptive Authority – Are Pharmacists “Write”?
The American population is obsessed with germs. Although relatively few people are unfortunate enough to suffer from OCD, a more pervasive subclinical paranoia persists in our psyche which manifests as our culture of cleanliness. During daytime television it is almost impossible to go through an entire commercial break without seeing an ad for cleaning products such as soaps, air sanitizers, detergents, or other various cleaning paraphernalia. Additionally, more and more of these products are emerging with some form of antimicrobial, antibacterial, or bacteriostatic chemical included to “stay tough on germs.” One such example is the chemical triclosan, although there are several others with similar issues. Read more →
In July 2008, results from several clinical trials of novel Alzheimer’s Disease treatments were presented at the Alzheimer’s Association International Conference on Alzheimer’s Disease (ICAD 2008) in Chicago. Among these results was an 84-week phase II trial of TauRx’s Rember. Almost immediately, the mainstream media was reporting the most critical breakthrough in the history of Alzheimer’s Disease. This enthusiasm may be premature, however, and more research is needed on this new treatment option. Read more →
Arguably, one of the greatest public health advances in the last century has been the advent of safe and effective vaccines for deadly diseases. Today, several vaccine-preventable diseases have all but disappeared from our lives, thanks to all 50 states mandating vaccination for school children and making routine vaccination a public health priority.
Children today receive dozens of doses of vaccines to prevent at least 16 illnesses throughout their infancy, childhood, and adolescence. For almost every child, these vaccines are safe and effective, leaving behind no more than a sore arm or leg for a few hours. However, the number of parents refusing vaccines for their children is rising. Read more →
The United States Food and Drug Administration (FDA) has evaluated the risk of suicide associated with antiepileptic drugs. The FDA examined 11 antiepileptic drugs, among nearly 28,000 patients, and found that patients taking an antiepileptic drug have an increased risk for suicidal behavior or ideation, compared to 16,000 patients receiving a placebo.
The FDA’s assessment consisted of reviewing 199 placebo-controlled trials evaluating the safety and efficacy of various antiepileptic drugs (also known as anticonvulsants). Read more →
I read with interest my fellow Brain Blogger’s article on pharmacists and their essential value to the medical team. While pharmacists do not have prescribing power and often get a bad rap as being “pill counters,” it is clear to me that their position in the medical team food chain is equivalent to having prescribing power.
At the very least, a good medical team or ICU team will have a pharmacist as part of the team to help with medications. This includes making sure the patient has no allergies, that there is no resistance or cross reactivity between medications, and checking to make sure the prescribed medication is clinically indicated. In this situation the pharmacist is sort of like the medical case manager. He or she “owns” the prescriptions of that team. Read more →
Pharmacists are integral members of the health care team in the US. The profession is composed of highly-educated, well-trained health-care providers. Pharmacists promote themselves as “drug experts” for good reason: the four-years of education required to obtain the Doctor of Pharmacy (PharmD) degree encompasses the etiology, pathophysiology, clinical manifestations, prevention, and management of human disease states. Pharmacists study the clinical application of pharmacology, biopharmaceutics, pharmacokinetics, therapeutics, adverse drug reactions, laboratory data, and drug information to the management of disease states. This training enables pharmacists to identify and prevent drug interactions, plan patient evaluation of drug-related problems and recommend changes in pharmaceutical care plans, and evaluate and interpret pharmaceutical data. Read more →
Monday, March 22, 2010
- Religion - A "Natural" Phenomenon?
- Psychotropics and Youth, Part 1 - The Five Myths
- How Culture Shapes Our Mind and Brain
- Sex, Violence and The Male Warrior Hypothesis
- The Secret to Good Health – Listen to the Data
- If Herbal Medicine is Medicine, Shouldn't it be Treated as Such?
- Neurology, Neurosurgery, and Neuroscience Conferences for 2010
- Too Much Information?
- "I Feel Your Pain" - The Neural Basis of Empathy
- Income Inequality and Health Outcomes
- The Evolution of Depression
- Journal Retracts Autism Research
- Speaking in Tongues - A Neural Snapshot
- Why Some Human Brains Become Leaders, While Others Followers?
- Post-Partum Psychosis - Rare but Real
- Is Your Doctor Happy or Burnt-Out?
- Worried Well on the Web
- Ginkgo Biloba Ineffective... Again
- Psychotropics and Youth, Part 2 - The Solutions
- Postoperative Cognitive Dysfunction
- Empathy – How Much is Too Much?
- Let the Matches Begin!
- My Nephew and his Brain, Part 4 – Their Life Today
- My Nephew and his Brain, Part 3 – Try to Work Out their Troubles
- My Nephew and his Brain, Part 2 – Revealed to be Complicated
- My Nephew and his Brain, Part 1 – Introduction
- Deep Brain Stimulation – A New Frontier in Psychiatry
- Psychotropics and Youth, Part 3 – Equip Teachers with Prescription Pads?
- Why Some Human Brains Become Leaders, While Others Followers?
- Brain Blogger Finalist for Two 2010 Research Blogging Awards in Neuroscience and Psychology
- Tall Tales of Diabetic Amputations
- Psychotropics and Youth, Part 2 – The Solutions
- Brain Blogging, Forty-Ninth Edition
- How Your Brain Groups Words
- The Child Brain and the Playing Teacher
- You Have a Right to Choose if we Agree
- Measuring Quality in Primary Care
- Matchmaker, Matchmaker Make Me A Match – The NRMP Main Residency Match
- Psychotropics and Youth, Part 1 – The Five Myths
- When It Comes to Aging, Size Matters
- i agree you dianne...
- Often, patients report persistent physical symptoms, but no somatic ...
- Great help, understood who is a LEADER & a FOLLOWER. Is there a category wh...
- Don't agree, to my opinion empathy is not easily learned, it's a quality not eve...
- Thanks, got the meaning of INTELLIGENCE/IQ....
- I'm a 54 yrs old woman .i was working for a retail company for 5 yrs ,my husbend...
- Thanks so much for sharing. My daughter began having seizures when she was 17. S...
- yea ur right lol lughter the best medicine i cnt do without it in a day!!!!!!!!!...
- Very touching story. My heart goes out to your family. Seizures are tough. And ...
- Thank you for sharing your nephew's story. So hard on those who love him, but I...
- Congratulations to all who've matched! Although the results of NRMP Main Residen...
- It's been almost 25 years since my son suffered a TBI in an accident. He was onl...
- I tend to agree with the teachers.But a teacher can only keep a record about the...
- Very interesting article, the 5th paragraph gets a little biased...but I still e...
- Dear Dan,There is certainly much clinical interest in this field. ClinicalTr...
- I recently commented on a sciencedaily.com article reporting success with TRD an...
- I have family members who are teachers. After sharing this article with them, th...
- It is great that people are challenging the use of this medication. As, a societ...
- I agree with the stand of the teachers and their children's that more than half ...
- I think that there’s also a social aspect to it. If you grow up in an area where...

