<?xml version="1.0" encoding="UTF-8"?> <rss version="2.0" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:wfw="http://wellformedweb.org/CommentAPI/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:atom="http://www.w3.org/2005/Atom" xmlns:sy="http://purl.org/rss/1.0/modules/syndication/" xmlns:slash="http://purl.org/rss/1.0/modules/slash/" ><channel><title>Brain Blogger &#187; Sudip Ghosh, MD</title> <atom:link href="http://brainblogger.com/author/sidg/feed/" rel="self" type="application/rss+xml" /><link>http://brainblogger.com</link> <description>Topics from multidimensional biopsychosocial perspectives.</description> <lastBuildDate>Sun, 21 Mar 2010 12:00:45 +0000</lastBuildDate> <generator>http://wordpress.org/?v=2.9.2</generator> <language>en</language> <sy:updatePeriod>hourly</sy:updatePeriod> <sy:updateFrequency>1</sy:updateFrequency> <item><title>Why Infidelity May Not Be Cheating Anymore</title><link>http://brainblogger.com/2008/11/11/why-infidelity-may-not-be-cheating-anymore/</link> <comments>http://brainblogger.com/2008/11/11/why-infidelity-may-not-be-cheating-anymore/#comments</comments> <pubDate>Tue, 11 Nov 2008 14:37:27 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Psychiatry & Psychology]]></category> <category><![CDATA[attachment]]></category> <category><![CDATA[Cheating]]></category> <category><![CDATA[cheats]]></category> <category><![CDATA[deviation]]></category> <category><![CDATA[faithful]]></category> <category><![CDATA[freedom]]></category> <category><![CDATA[Infidelity]]></category> <category><![CDATA[Montreal]]></category> <category><![CDATA[norm]]></category> <category><![CDATA[relationship]]></category> <category><![CDATA[research]]></category> <category><![CDATA[social evolution]]></category> <category><![CDATA[study]]></category> <category><![CDATA[universal attachment]]></category><guid isPermaLink="false">http://brainblogger.com/?p=1738</guid> <description><![CDATA[Cheating implies some sort of deviation form the norm &#8212; staying faithful. But as new research suggests, the chances of infidelity in a relationship now varies between 40 and 76%; and this implies that infidelity itself could be the new norm. &#8220;It&#8217;s very high,&#8221; according to researcher Genevieve Beaulieu-Pelletier, a PhD candidate at the Universite de [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/psychiatry-and-psychology-brain-blogger.jpg" title="Psychiatry and Psychology Category" width="290" height="200" class="left" />Cheating implies some sort of deviation form the norm &#8212; staying faithful. But as new research suggests, the chances of infidelity in a relationship now varies between 40 and 76%; and this implies that infidelity itself could be the new norm.</p><p>&#8220;It&#8217;s very high,&#8221; according to researcher Genevieve Beaulieu-Pelletier, a PhD candidate at the Universite de Montreal&#8217;s Department of Psychology and author of this new study. According to her findings, people with avoidant-attachment styles are particularly likely to have multiple sexual encounters, and they are afraid of intimacy. She collated her results from two different studies, one on 145 students and the other on 270 adults with the same results.</p><p><img src="http://farm3.static.flickr.com/2157/2263962161_ececc1e94e_m.jpg" alt="Couple" class="right" />The explanation for avoidance-attachment is often sought in childhood, as a direct result of inadequate parenting. In adult life, in order to prevent commitment-phobia many of these individuals in relationships cheat to reassure themselves of their own space and freedom. As a followup to the previous studies, two further studies revealed that the number one motive quoted as a reason for infidelity was a conscious will to distance oneself from commitment and one&#8217;s partner.</p><p>Does this imply that frighteningly, large segments of humanity have become attachment avoidant,  which could increasingly become a universal trend. It is quite possible that things may shape that way in the future with increased emphasis on personal freedom, and less on one&#8217;s ties with the community and family. The study found that men and women were equally likely to display infidelity, and for exactly the same reasons.</p><p>With such high numbers of self-confessed &#8220;cheats&#8221; in the study, it is clear that infidelity no longer provokes the same kind of moralistic sentiments than it used to, even 50 years ago. And if it becomes an accepted norm, it might well usher in the next step in our social evolution &#8212; universal attachment &#8212; avoidance.</p><p><strong>Reference</strong></p><p><a href="http://nouvelles.umontreal.ca/content/view/1629/124/">Infidelity dissected: New research on why people cheat</a>. University of Montreal, September 8, 2008.</p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/11/11/why-infidelity-may-not-be-cheating-anymore/feed/</wfw:commentRss> <slash:comments>6</slash:comments> </item> <item><title>The Scent Trail &#8211; Encoding Memory</title><link>http://brainblogger.com/2008/10/24/the-scent-trail-encoding-memory/</link> <comments>http://brainblogger.com/2008/10/24/the-scent-trail-encoding-memory/#comments</comments> <pubDate>Fri, 24 Oct 2008 15:54:44 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Neuroscience & Neurology]]></category> <category><![CDATA[behavior]]></category> <category><![CDATA[behavioral changes]]></category> <category><![CDATA[cerebral cortex]]></category> <category><![CDATA[childhood]]></category> <category><![CDATA[Encoding]]></category> <category><![CDATA[Marcel Proust]]></category> <category><![CDATA[memory]]></category> <category><![CDATA[noradrenaline]]></category> <category><![CDATA[novel]]></category> <category><![CDATA[olfactory]]></category> <category><![CDATA[role]]></category> <category><![CDATA[understanding]]></category><guid isPermaLink="false">http://brainblogger.com/?p=1732</guid> <description><![CDATA[Marcel Proust&#8217;s 3,200 page novel À la recherche du temps perdu has in it the famous scene where dipping pastry into his tea flooded him with his childhood memories. It was the odor which provoked it, and it has gone into psychoanalytical literature as the most famous literary evidence of the power of scents in [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/neuroscience-and-neurology-brain-blogger.jpg" title="Neuroscience and Neurology Category" width="290" height="200" class="left" />Marcel Proust&#8217;s 3,200 page novel <em>À la recherche du temps perdu</em> has in it the famous scene where dipping pastry into his tea flooded him with his childhood memories. It was the odor which provoked it, and it has gone into psychoanalytical literature as the most famous literary evidence of the power of scents in retrieving long-lost memories.</p><p>In a recent controlled study over sleeping mice at the Duke University Medical Center, neuroscientists Stephen Shea and Richard Mooney have tried to elucidate the cellular and molecular basis of how memory of scents are locked up in the brain, only to be retrieved later years afterward, and provoking a strong recall of original incidents. While asleep the animals were administered electric shocks which triggered noradrenaline release; at the same time strong odors were presented to their noses: of food and urine of other mice. The study published in a recent edition of <em>Neuroscience</em> is an important milestone in our understanding of odor-processing.</p><p><img src="http://farm1.static.flickr.com/49/134450974_7af61cf994_m.jpg" alt="White flowers" class="right" />Later when awake, the introduction of the same odors provoked distinct behavioral changes, proving that in the presence of adrenaline, odors are codified as memory traces, even though they were asleep. It was an earlier hypothesis which this study lends support to, that noradrenaline plays an important role in preserving memories of scents due to processing in the olfactory bulb in both humans and mice. Long lasting memories are very important for social bonding and this study may have implications for understanding how long lasting memories are linked with emotion. While odors are thought to be extremely important in the social behavior of many animals, in humans its role is still not well understood. Part of this is due to the fact that in humans, the cerebral cortex has assumed an over-riding importance compared to the brains of animals lower down the evolutionary scale.</p><p>However, there are many amongst us who remain Proustian at heart, and odors are emotionally important. The waft of Mother&#8217;s rhubarb pie may remain an important link to her in the future, long after she is gone.</p><p><strong>Reference</strong></p><p><span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.jtitle=Journal+of+Neuroscience&#038;rft.id=info:DOI/10.1523%2FJNEUROSCI.3853-08.2008&#038;rft.atitle=Noradrenergic+Induction+of+Odor-Specific+Neural+Habituation+and+Olfactory+Memories&#038;rft.date=2008&#038;rft.volume=28&#038;rft.issue=42&#038;rft.spage=10711&#038;rft.epage=10719&#038;rft.artnum=http%3A%2F%2Fwww.jneurosci.org%2Fcgi%2Fdoi%2F10.1523%2FJNEUROSCI.3853-08.2008&#038;rft.au=S.+D.+Shea&#038;rft.au=L.+C.+Katz&#038;rft.au=R.+Mooney&#038;bpr3.included=1&#038;bpr3.tags=">S. D. Shea, L. C. Katz, R. Mooney (2008). Noradrenergic Induction of Odor-Specific Neural Habituation and Olfactory Memories <span style="font-style: italic;">Journal of Neuroscience, 28</span> (42), 10711-10719 DOI: <a rev="review" href="http://dx.doi.org/10.1523/JNEUROSCI.3853-08.2008">10.1523/JNEUROSCI.3853-08.2008</a></span></p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/10/24/the-scent-trail-encoding-memory/feed/</wfw:commentRss> <slash:comments>2</slash:comments> </item> <item><title>Killer Anti-Oxidant Vitamins: When Excess Could Be Exceedingly Dangerous</title><link>http://brainblogger.com/2008/04/28/killer-anti-oxidant-vitamins-when-excess-could-be-dangerous/</link> <comments>http://brainblogger.com/2008/04/28/killer-anti-oxidant-vitamins-when-excess-could-be-dangerous/#comments</comments> <pubDate>Mon, 28 Apr 2008 14:24:44 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Articles & Studies]]></category> <category><![CDATA[cancer]]></category> <category><![CDATA[clinical nutrition]]></category> <category><![CDATA[death]]></category> <category><![CDATA[fish oil]]></category> <category><![CDATA[intake]]></category> <category><![CDATA[lung cancer]]></category> <category><![CDATA[nutrition]]></category> <category><![CDATA[study]]></category> <category><![CDATA[sunflower oil]]></category> <category><![CDATA[supplementation]]></category> <category><![CDATA[vitamin]]></category> <category><![CDATA[Vitamin A]]></category> <category><![CDATA[Vitamin C]]></category> <category><![CDATA[Vitamin E]]></category><guid isPermaLink="false">http://brainblogger.com/?p=822</guid> <description><![CDATA[Vitamin E today ranks as the second highest single vitamin consumed in the world after vitamin C, following well organized marketing campaigns extolling its anti-oxidative properties. Anti-oxidation is today a key marketing buzzword for the growing market segment of anti-aging dietary supplements, although how it affects human life spans is poorly understood. According to Wellcome [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/articles-and-studies-brain-blogger.jpg" alt="Articles_Studies.jpg" title="Articles_Studies.jpg" class="left" width="290" height="200" />Vitamin E today ranks as the second highest single vitamin consumed in the world after vitamin C, following well organized marketing campaigns extolling its anti-oxidative properties. Anti-oxidation is today a key marketing buzzword for the growing market segment of anti-aging dietary supplements, although how it affects human life spans is poorly understood. According to Wellcome Trust [1] there is no evidence in humans that anti-oxidative vitamins (A, C and E) slows aging; only in laboratory mice have they led to a sight increase in lifespan. Nevertheless, these vitamins are widely sold today without prescription as tablets, fish oils and capsules across chemists, superstores and even eBay.</p><p>Brand new research [2] from a study of over 77,000 people has shown that higher than recommended doses of Vitamin E can lead to a &#8220;significant&#8221; increase in the risk of developing lung cancer, irrespective of whether they smoked or not. The strength of the findings was somewhat unexpected &#8212; a 7% rise in lung cancer for every extra 100 mg of Vitamin E taken daily for 10 years. With an average daily Vitamin E supplement of 400 mg, this could mean a 28% excess risk for someone to develop lung cancer taking just one pill a day.</p><p><img src="http://farm1.static.flickr.com/61/189787478_91ddbf325e_m.jpg" alt="Vitamins" class="right" />An important question is: do we need Vitamin E supplementation at all on top of an average diet? The UK Food Standard Agency website estimates daily dietary requirements of Vitamin E to be just 4 mg for men and 3 mg for women. It also mentions that not enough is known about the side-effects of high-dose vitamin E supplements, and that 540 mg or less a day is &#8220;unlikely&#8221; to be harmful. This new study could change all that.</p><p>While the protective effects of Vitamin E against heart disease and many forms of cancer are acknowledged, dietary deficiency is rare today [3]. This is mainly related to the fact that vitamin E intake in modern diets is mainly dependent on polyunsaturated fatty acids, and with diets rich in vegetable oils and green leafy vegetables, the amount of daily vitamin E intake could well exceed 20-40 mg &#8212; just a tablespoon of sunflower oil has 6 mg, while wheatgerm oil has 20 mg or so.</p><p>Do we actually need any extra vitamin E supplements if we can make up for our daily requirement through diet? An editorial from the American Journal of Clinical Nutrition in 2006 [4] concluded that intervention studies did not support a beneficial effect of antioxidant supplements, and there was a growing body of evidence that with anti-oxidant vitamins, &#8220;just enough&#8221; was more than adequate. About 15 mg per day of Vitamin E was enough to provide us with maximum protection against chronic disease, according to the journal.</p><p><img src="http://farm1.static.flickr.com/65/155517365_30e4f8e2e9_m.jpg" alt="Death Valley" class="right" />The debate about Vitamin E supplementation as a potential cause of premature death is however not new. In 2004, the Times [5] reported the results from a John Hopkins study [6] that pooled the result of 19 studies on vitamin E supplementation worldwide. The study found that doses of 400 international units (IU) of Vitamin E, &#8220;often the equivalent of a single capsule were associated with a 10% increased risk of death.&#8221; Ominously, the study found that many people were taking as much as 400-800 mg of Vitamin E a day. Even the Lancet had earlier estimated that out of a million people taking Vitamin E supplements, 9,000 were expected to die premature deaths.</p><p>The question therefore is not &#8220;if,&#8221; but rather &#8220;how much.&#8221; Supplementation can increase the intake of Vitamin E by up to a hundred times of that of daily requirements, and as the latest study shows, the increase in risk of lung cancer can also be substantial. Dietary adjustment can well increase our intake of Vitamin E to well above our recommended daily allowances. The question therefore remains: is it at all justifiable to use &#8220;killer&#8221; doses of a supplement that has no demonstrable benefits at all above its physiological limits?</p><p><strong>References</strong></p><p>1. Wellcome Trust. <a href="http://www.wellcome.ac.uk/Professional-resources/Education-resources/Big-Picture/Ageing/Articles/wtd004289.htm">Anti-ageing treatments.</a></p><p>2. <span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=Byers&#038;rft.aufirst=T&#038;rft.au=T+ Byers&#038;rft.title=American+Journal+of+Respiratory+and+Critical+Care+Medicine&#038;rft.atitle=Nutrition+and+Lung+Cancer%3A+Lessons+from+the+Differing+Effects+of+Foods+and+Supplements&#038;rft.date=2007&#038;rft.volume=177&#038;rft.issue=5&#038;rft.spage=470&#038;rft.epage=471&#038;rft.genre=article&#038;rft.id=info:DOI/10.1164%2Frccm.200711-1681ED"></span>Byers, T. (2007). Nutrition and Lung Cancer: Lessons from the Differing Effects of Foods and Supplements. <span style="font-style: italic;">American Journal of Respiratory and Critical Care Medicine, 177</span>(5), 470-471. DOI: <a rev="review" href="http://dx.doi.org/10.1164/rccm.200711-1681ED">10.1164/rccm.200711-1681ED</a></p><p>3. British Nutrition Foundation. (2004). <a href="http://www.nutrition.org.uk/home.asp?siteId=43&#038;sectionId=604&#038;subSubSectionId=324&#038;subSectionId=320&#038;parentSection=299&#038;which=1">Vitamins</a>.</p><p>4. <span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=Traber&#038;rft.aufirst=Margert&#038;rft.aumiddle=G&#038;rft.au=Margert+ Traber&#038;rft.title=American+Journal+of+Clinical+Nutrition&#038;rft.atitle=How+much+vitamin+E%3F+...+Just+enough%21&#038;rft.date=2006&#038;rft.volume=84&#038;rft.issue=5&#038;rft.spage=959&#038;rft.epage=960&#038;rft.genre=article&#038;rft.id=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F17093143&#038;rft.id=info:PMID/17093143"></span>Traber, M.G. (2006). <a href="http://www.ncbi.nlm.nih.gov/pubmed/17093143">How much vitamin E? &#8230; Just enough!</a> <span style="font-style: italic;">American Journal of Clinical Nutrition, 84</span>(5), 959-960.</p><p>5. Lister, S. (2004). <a href="http://www.timesonline.co.uk/tol/news/uk/article1076894.ece">The vitamin boost that could cause early death</a>. <em>TimesOnline</em>.</p><p>6. <span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=MILLERIII&#038;rft.aufirst=E&#038;rft.au=E+ MILLERIII&#038;rft.au=R+PASTORBARRIUSO&#038;rft.au=D+DALAL&#038;rft.au=R+RIEMERSMA&#038;rft.au=L+APPEL&#038;rft.au=E+GUALLAR&#038;rft.title=ACC+Current+Journal+Review&#038;rft.atitle=Meta-Analysis%3A+High-Dosage+Vitamin+E+Supplementation+May+Increase+All-Cause+Mortality&#038;rft.date=2005&#038;rft.volume=14&#038;rft.issue=5&#038;rft.spage=17&#038;rft.epage=17&#038;rft.genre=article&#038;rft.id=info:DOI/10.1016%2Fj.accreview.2005.04.017"></span>MILLER, E., PASTORBARRIUSO, R., DALAL, D., RIEMERSMA, R., APPEL, L., GUALLAR, E. (2005). Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality. <span style="font-style: italic;">ACC Current Journal Review, 14</span>(5), 17-17. DOI: <a rev="review" href="http://dx.doi.org/10.1016/j.accreview.2005.04.017">10.1016/j.accreview.2005.04.017</a></p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/04/28/killer-anti-oxidant-vitamins-when-excess-could-be-dangerous/feed/</wfw:commentRss> <slash:comments>4</slash:comments> </item> <item><title>How Yoga Improves Balance in the Elderly</title><link>http://brainblogger.com/2008/04/24/how-yoga-improves-balance-in-the-elderly/</link> <comments>http://brainblogger.com/2008/04/24/how-yoga-improves-balance-in-the-elderly/#comments</comments> <pubDate>Thu, 24 Apr 2008 14:33:12 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Alternative Medicine]]></category> <category><![CDATA[Balance]]></category> <category><![CDATA[cerebellar responses]]></category> <category><![CDATA[confidence]]></category> <category><![CDATA[Gait]]></category> <category><![CDATA[improvement]]></category> <category><![CDATA[mobility]]></category> <category><![CDATA[podiatry]]></category> <category><![CDATA[spinal reflexes]]></category> <category><![CDATA[study]]></category> <category><![CDATA[yoga]]></category><guid isPermaLink="false">http://brainblogger.com/?p=862</guid> <description><![CDATA[Amongst older adults aged 65 and over, falls are the leading cause of non-fatal injuries and hospital admissions. It is estimated that at least one-third of adults above 65 experience serious falls in their lifetime. The cause of falls in the elderly is often multi-factorial, and no definite cause is ascertainable in the vast majority. [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/alternative-medicine-brain-blogger.jpg" alt="Alternative_Medicine2.jpg" title="Alternative_Medicine2.jpg" class="left" width="290" height="200" />Amongst older adults aged 65 and over, falls are the leading cause of non-fatal injuries and hospital admissions. It is estimated that at least one-third of adults above 65 experience serious falls in their lifetime. The cause of falls in the elderly is often multi-factorial, and no definite cause is ascertainable in the vast majority. Quite often balance system in-coordination is pointed out, but as an integrated system, balance relies on inputs from various sources: vision, cerebellar responses, joint senses and even basic spinal reflexes.</p><p><img src="http://farm1.static.flickr.com/48/151075485_15a57a8fc0_m.jpg" alt="Yoga" class="right" />A new study from Temple University&#8217;s <a href="http://podiatry.temple.edu/gaitlab/index.html">Gait Study Center</a> has found that Yoga helps with both balance and stability, and effectively reduces the chance of major falls in the elderly. Dr. Jinsup Song and his colleagues at the School of Podiatric Medicine and the College of Health Professions studied the effects of a specifically designed Iyengar Yoga program on 24 volunteers &#8212; women in the over-65 age group. After completing the nine week program, all participants reported a faster stride, an improvement in single leg stance and confidence in walking and balancing and improved flexibility in the lower limbs. In addition, participants became much better at how to redistribute pressure through the soles of their feet.</p><p>Some participants even reported improvement in their pain symptoms as a result of reduced stress on their arthritic joints. In addition, the study found that participants reported a more optimistic, focussed, goal-oriented view of life. For the elderly, this means a vastly improved confidence in balancing themselves and increasing their mobility, which in turn helps to prevent falls.</p><p>Perhaps this study elegantly demonstrates that falls in the elderly are often a result of disuse of their balance capabilities, which can be greatly enhanced through professional programs.</p><p><strong>Reference</strong></p><p><span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=Song&#038;rft.aufirst=J&#038;rft.au=J+ Song&#038;rft.au=R+Newton&#038;rft.au=J+Yun&#038;rft.au=B+Heilman&#038;rft.au=E+Zoltick&#038;rft.title=the+Gait+and+Clinical+Movement+Analysis+Society+Proceedings&#038;rft.atitle=Gait+Study+Center&#038;rft.date=2008&#038;rft.volume=&#038;rft.issue=&#038;rft.spage=&#038;rft.genre=article"></span>Song, J., Newton, R., Yun, J.S., Heilman, B., Zoltick, E. (2008). Gait Study Center. <span style="font-style: italic;">Gait and Clinical Movement Analysis Society Proceedings.</span></p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/04/24/how-yoga-improves-balance-in-the-elderly/feed/</wfw:commentRss> <slash:comments>3</slash:comments> </item> <item><title>Functional MRI: Emerging Uses for Neurological Diseases &#8211; Part 2</title><link>http://brainblogger.com/2008/04/03/functional-mri-emerging-uses-for-neurological-illnesses-part-ii/</link> <comments>http://brainblogger.com/2008/04/03/functional-mri-emerging-uses-for-neurological-illnesses-part-ii/#comments</comments> <pubDate>Fri, 04 Apr 2008 06:52:11 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Neuroscience & Neurology]]></category> <category><![CDATA[Alzheimers]]></category> <category><![CDATA[brain tumor]]></category> <category><![CDATA[fmri]]></category> <category><![CDATA[functional MRI]]></category> <category><![CDATA[neuroimaging]]></category> <category><![CDATA[neurology]]></category> <category><![CDATA[neurosurgery]]></category> <category><![CDATA[pain management]]></category> <category><![CDATA[pharmacological MRI]]></category> <category><![CDATA[phMRI]]></category> <category><![CDATA[radiology]]></category> <category><![CDATA[schizophrenia]]></category> <category><![CDATA[stroke]]></category> <category><![CDATA[surgery]]></category> <category><![CDATA[technology]]></category> <category><![CDATA[tumor]]></category><guid isPermaLink="false">http://brainblogger.com/?p=825</guid> <description><![CDATA[Despite the fact that functional MRI was discovered in the early 90&#8217;s, scientific research related to its clinical applications is still at an early stage. The first paper on the use of functional MRI (fMRI) in Alzheimer&#8217;s disease came out as late as 1999. Today, fMRI is being intensively studied in a number of other [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/neuroscience-and-neurology-brain-blogger.jpg" alt="Neuroscience_Neurology.jpg" title="Neuroscience_Neurology.jpg" class="left" width="290" height="200" />Despite the fact that <a href="http://brainblogger.com/2008/03/19/functional-mri-a-radiological-window-into-the-mind-part-1/">functional MRI</a> was discovered in the early 90&#8217;s, scientific research related to its clinical applications is still at an early stage. The first paper on the use of functional MRI (fMRI) in Alzheimer&#8217;s disease came out as late as 1999. Today, fMRI is being intensively studied in a number of other clinical areas like dyslexia, epilepsy, mood and anxiety disorders, pain management, rehabilitation after stroke and schizophrenia. Though the application of fMRI in routine neurological practice is still some years away, already our understanding of these disorders and knowledge about mapping progression and treatment effects with fMRI is rapidly progressing.</p><p>Alcohol and substance abuse, for example is another developing area. Studying the effect of pharmacological substances on MRI blood flow patterns is spearheaded by the rapidly growing area of pharmacological MRI (phMRI). Updated models of craving and addiction incorporating fMRI criteria demonstrate that over the course of addiction, as it becomes chronic, an orderly change in brain blood flow patterns sets in, as more and more areas get involved.</p><p>Pre-surgical planning with functional neuroimaging has been undergoing evaluation over the past few years, particularly in cases involving resections of brain tumors and arterio-venous malformations, as well as in surgery for epilepsy. One important problem with these procedures is the collateral damage inflicted by surgery on vitally important structures and tracts in the vicinity of the lesion. By a pre-operative fMRI evaluation, it is relatively easy to visualize what cognitive, motor or sensory functions are likely to be impaired following the resection, and counsel the patient accordingly. In addition a pre-operative &#8216;functional&#8217; map might guide surgeons to limit the extent of damage by making them aware of the proximity of functionally important areas. One study found pre-surgical fMRI useful in 89% of tumor and 91% of epilepsy surgical patients.</p><p>The future for fMRI is bright. While the technology is still improving, there is a lot of research that needs to be done, along with statistical validation of brain maps from various sources. But it is already leading to a paradigm shift in our understanding of how the brain works in real-time, and perhaps for the first time, we have developed a visual probe in to our minds. As the logical next step, we are standing on the threshold of a new approach to the clinical practice of neurology and its allied behavioral sciences.</p><p><strong>References</strong></p><p><span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=Ogawa&#038;rft.aufirst=S&#038;rft.au=S+ Ogawa&#038;rft.title=Proceedings+of+the+National+Academy+of+Sciences&#038;rft.atitle=Brain+Magnetic+Resonance+Imaging+with+Contrast+Dependent+on+Blood+Oxygenation&#038;rft.date=1990&#038;rft.volume=87&#038;rft.issue=24&#038;rft.spage=9868&#038;rft.epage=9872&#038;rft.genre=article&#038;rft.id=info:DOI/10.1073%2Fpnas.87.24.9868"></span>Ogawa, S. (1990). Brain Magnetic Resonance Imaging with Contrast Dependent on Blood Oxygenation. <span style="font-style: italic;">Proceedings of the National Academy of Sciences, 87</span>(24), 9868-9872. DOI: <a rev="review" href="http://dx.doi.org/10.1073/pnas.87.24.9868">10.1073/pnas.87.24.9868</a></p><p><span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=Small&#038;rft.aufirst=Scott&#038;rft.aumiddle=A&#038;rft.au=Scott+ Small&#038;rft.au=Gerard+M+Perera&#038;rft.au=Robert++DeLapaz&#038;rft.au=Richard++Mayeux&#038;rft.au=Yaakov++Stern&#038;rft.title=Annals+of+Neurology&#038;rft.atitle=Differential+regional+dysfunction+of+the+hippocampal+formation+among+elderly+with+memory+decline+and+Alzheimer%27s+disease&#038;rft.date=2001&#038;rft.volume=45&#038;rft.issue=4&#038;rft.spage=466&#038;rft.epage=472&#038;rft.genre=article&#038;rft.id=info:DOI/10.1002%2F1531-8249%28199904%2945%3A4%3C466%3A%3AAID-ANA8%3E3.0.CO%3B2-Q"></span>Small, S.A., Perera, G.M., DeLapaz, R., Mayeux, R., Stern, Y. (2001). Differential regional dysfunction of the hippocampal formation among elderly with memory decline and Alzheimer&#8217;s disease. <span style="font-style: italic;">Annals of Neurology, 45</span>(4), 466-472. DOI: <a rev="review" href="http://tinyurl.com/2zerbn">10.1002/1531-8249(199904)45:4<466::AID-ANA8>3.0.CO;2-Q</a></p><p><span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=PORRINO&#038;rft.aufirst=L&#038;rft.au=L+ PORRINO&#038;rft.au=H+SMITH&#038;rft.au=M+NADER&#038;rft.au=T+BEVERIDGE&#038;rft.title=Progress+in+Neuro-Psychopharmacology+and+Biological+Psychiatry&#038;rft.atitle=The+effects+of+cocaine%3A+A+shifting+target+over+the+course+of+addiction&#038;rft.date=2007&#038;rft.volume=31&#038;rft.issue=8&#038;rft.spage=1593&#038;rft.epage=1600&#038;rft.genre=article&#038;rft.id=info:DOI/10.1016%2Fj.pnpbp.2007.08.040"></span>PORRINO, L., SMITH, H., NADER, M., BEVERIDGE, T. (2007). The effects of cocaine: A shifting target over the course of addiction. <span style="font-style: italic;">Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31</span>(8), 1593-1600. DOI: <a rev="review" href="http://dx.doi.org/10.1016/j.pnpbp.2007.08.040">10.1016/j.pnpbp.2007.08.040</a></p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/04/03/functional-mri-emerging-uses-for-neurological-illnesses-part-ii/feed/</wfw:commentRss> <slash:comments>0</slash:comments> </item> <item><title>The Brain-Road Link: New Evidence on Cell Phones and Driving</title><link>http://brainblogger.com/2008/03/28/the-brain-road-link-new-evidence-on-cell-phones-and-driving/</link> <comments>http://brainblogger.com/2008/03/28/the-brain-road-link-new-evidence-on-cell-phones-and-driving/#comments</comments> <pubDate>Fri, 28 Mar 2008 16:29:50 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Neuroscience & Neurology]]></category> <category><![CDATA[blood flow]]></category> <category><![CDATA[blood flows]]></category> <category><![CDATA[brain research]]></category> <category><![CDATA[carnegie mellon]]></category> <category><![CDATA[different parts of the brain]]></category> <category><![CDATA[flow patterns]]></category> <category><![CDATA[fmri]]></category> <category><![CDATA[hands free kits]]></category> <category><![CDATA[high speeds]]></category> <category><![CDATA[law enforcers]]></category> <category><![CDATA[milliseconds]]></category> <category><![CDATA[neuronal circuits]]></category> <category><![CDATA[occipital cortex]]></category> <category><![CDATA[parietal cortex]]></category> <category><![CDATA[parts of the brain]]></category> <category><![CDATA[road hazards]]></category> <category><![CDATA[road safety]]></category> <category><![CDATA[spatial awareness]]></category> <category><![CDATA[spatial cues]]></category> <category><![CDATA[university of oregon]]></category><guid isPermaLink="false">http://brainblogger.com/2008/03/28/the-brain-road-link-new-evidence-on-cell-phones-and-driving/</guid> <description><![CDATA[Law enforcers now have all the proof they need for tougher anti-cell phone measures for drivers, as the latest published neurological study shows that there is a 37% reduction in parietal cortex activity with driving. Arguments that there are many among us who can multi-task well have taken a back seat in recent studies involving [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/neuroscience-and-neurology-brain-blogger.jpg" alt="Neuroscience_Neurology2.jpg" title="Neuroscience_Neurology2.jpg" class="left" width="290" height="200" />Law enforcers now have all the proof they need for tougher anti-cell phone measures for drivers, as the latest published neurological study shows that there is a 37% reduction in parietal cortex activity with driving. Arguments that there are many among us who can multi-task well have taken a back seat in recent studies involving driving and mobile phone listening.</p><p>An University of Oregon Study in 2005 found that complex skills like driving do not only include motor skills, but also staying receptive of visual and spatial cues from minute to minute. It estimated that conversing on the cell phone can increase a driver&#8217;s response time by up to 800 milliseconds, and at 60 miles per hour that could mean a significantly higher risk to drivers responding to road hazards.</p><p>This new study from Carnegie Mellon, reported in a recent issue of Brain Research however takes it a step further. It suggests that it just might not be enough to use voice-activated systems or hands-free kits for road safety &#8212; we have to put our brains too on the road. Carried out on 29 volunteers, the study measured changes in brain blood flow patterns using functional MRI (fMRI) as they simulated driving realistically in the laboratory.</p><p>There was a 37% reduction in blood flow through the parietal cortex as a result of driving, which is the seat of spatial sensation and navigation in the brain. For drivers a reduction in spatial awareness could prove fatal, as their ability to carry out defensive and avoidance maneuvers at high speeds could be seriously compromised. In fact, a significant deterioration in the quality of driving was noticed in the study &#8212; even though the participants were only &#8220;listening&#8221;. Listening and driving depend on so different parts of the brain, that the neuronal circuits are bound to experience a &#8220;clash of interests&#8221; so to speak, when it comes to blood flows and activity. The study also found significant deficits in the occipital cortex, which could be linked to visual inattention of the road ahead &#8212; another potentially dangerous factor.</p><p>Well, not much of an argument over this study I believe, even if you are an excellent, proven multi-tasker.</p><p><strong>References</strong></p><p><span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=Lien&#038;rft.aufirst=Mei-Ching&#038;rft.au=Mei-Ching+ Lien&#038;rft.au=Robert+McCann&#038;rft.au=Eric+Ruthruff&#038;rft.au=Robert+Proctor&#038;rft.title=Journal+of+Experimental+Psychology%3A+Human+Perception+and+Performance&#038;rft.atitle=Dual-Task+Performance+With+Ideomotor-Compatible+Tasks%3A+Is+the+Central+Processing+Bottleneck+Intact%2C+Bypassed%2C+or+Shifted+in+Locus%3F&#038;rft.date=2005&#038;rft.volume=31&#038;rft.issue=1&#038;rft.spage=122&#038;rft.epage=144&#038;rft.genre=article&#038;rft.id=info:DOI/10.1037%2F0096-1523.31.1.122"></span>Lien, M., McCann, R.S., Ruthruff, E., Proctor, R.W. (2005). Dual-Task Performance With Ideomotor-Compatible Tasks: Is the Central Processing Bottleneck Intact, Bypassed, or Shifted in Locus?. <span style="font-style: italic;">Journal of Experimental Psychology: Human Perception and Performance, 31</span>(1), 122-144. DOI: <a rev="review" href="http://dx.doi.org/10.1037/0096-1523.31.1.122">10.1037/0096-1523.31.1.122</a></p><p><a href="http://www.cmu.edu/news/archive/2008/March/march5_drivingwhilelistening.shtml">Carnegie Mellon Study Shows Just Listening To Cell Phones Significantly Impairs Drivers</a>. Carnegie Mellon University &#8211; Press Release.</p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/03/28/the-brain-road-link-new-evidence-on-cell-phones-and-driving/feed/</wfw:commentRss> <slash:comments>0</slash:comments> </item> <item><title>The &#8220;Art&#8221; of Being Smart</title><link>http://brainblogger.com/2008/03/25/the-art-of-being-smart/</link> <comments>http://brainblogger.com/2008/03/25/the-art-of-being-smart/#comments</comments> <pubDate>Tue, 25 Mar 2008 18:38:46 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Neuroscience & Neurology]]></category> <category><![CDATA[aesthetics]]></category> <category><![CDATA[attention skills]]></category> <category><![CDATA[brain research]]></category> <category><![CDATA[candidate genes]]></category> <category><![CDATA[dance education]]></category> <category><![CDATA[dr michael]]></category> <category><![CDATA[geometrical representation]]></category> <category><![CDATA[individual differences]]></category> <category><![CDATA[language skills]]></category> <category><![CDATA[mainstream science]]></category> <category><![CDATA[memory enhancement]]></category> <category><![CDATA[memory retrieval]]></category> <category><![CDATA[music drama]]></category> <category><![CDATA[music training]]></category> <category><![CDATA[neural pathways]]></category> <category><![CDATA[school curricula]]></category> <category><![CDATA[science and humanities]]></category> <category><![CDATA[split brain]]></category> <category><![CDATA[university of california at santa barbara]]></category> <category><![CDATA[unrelated areas]]></category><guid isPermaLink="false">http://brainblogger.com/2008/03/25/the-art-of-being-smart/</guid> <description><![CDATA[A three-year multicenter study called Learning, Arts, and the Brain is finally close to solving the problem of whether art makes us smarter or whether smarter people are drawn to arts. The question is not purely rhetorical, as in recent years educationists have debated about the relevance of arts in modern school curricula; whether music, drama [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/neuroscience-and-neurology-brain-blogger.jpg" alt="Neuroscience_Neurology.jpg" title="Neuroscience_Neurology.jpg" class="left" width="290" height="200" />A three-year multicenter study called <em>Learning, Arts, and the Brain</em> is finally close to solving the problem of whether art makes us smarter or whether smarter people are drawn to arts.</p><p>The question is not purely rhetorical, as in recent years educationists have debated about the relevance of arts in modern school curricula; whether music, drama and dance education should be given an equal emphasis compared to more mainstream science and humanities subjects. In particular some of the key issues raised were related to the attention skills and processes of memory retrieval that is unique to those who appreciate art, and can be put to use in other areas of academics as well.</p><p>The study led by Dr Michael Gazzaniga (famous for his work on split-brain research) of the University of California at Santa Barbara utilized brain scanning and behavioral studies to examine a number of questions in this regard. An interest in the arts has been found to lead to high levels of attention that improves performance in many other areas. In particular music training leads to memory enhancement in several unrelated areas too. A link has been found in children between music training and ability in geometrical representation of concepts and ideas, apart from development of neural pathways for phonological awareness.  Phonologically aware children have been shown to develop superior learning skills and language skills.</p><p>On the other hand, learning to dance is also distinctly advantageous as it leads to a better capacity for learning complex patterns of behavior. The other important find in this study, involving seven universities, was the presence of candidate genes that are responsible for our individual differences in affinity for art. In adults dopamine-related genes have been found to be associated with an interest in the aesthetics and &#8220;open&#8221; personalities, as artists often are.</p><p>It would appear then that art is a deeply neurological phenomenon &#8212; much more than most of us think.</p><p><strong>Reference</strong></p><p>Michael S. Gazzaniga. <a href="http://www.dana.org/news/publications/publication.aspx?id=10760">Learning, Arts, and the Brain</a>. <em>The Dana Consortium Report</em>. 2008.</p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/03/25/the-art-of-being-smart/feed/</wfw:commentRss> <slash:comments>0</slash:comments> </item> <item><title>Functional MRI: A Radiological Window into the Mind &#8211; Part 1</title><link>http://brainblogger.com/2008/03/19/functional-mri-a-radiological-window-into-the-mind-part-1/</link> <comments>http://brainblogger.com/2008/03/19/functional-mri-a-radiological-window-into-the-mind-part-1/#comments</comments> <pubDate>Wed, 19 Mar 2008 14:22:14 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Neuroscience & Neurology]]></category> <category><![CDATA[brain scan]]></category> <category><![CDATA[color feature]]></category> <category><![CDATA[conceptual domains]]></category> <category><![CDATA[different parts of the brain]]></category> <category><![CDATA[experimental tools]]></category> <category><![CDATA[flow patterns]]></category> <category><![CDATA[fmri]]></category> <category><![CDATA[human brain]]></category> <category><![CDATA[human brains]]></category> <category><![CDATA[left half]]></category> <category><![CDATA[linguistic features]]></category> <category><![CDATA[neuroscientist]]></category> <category><![CDATA[objective data]]></category> <category><![CDATA[parts of the brain]]></category> <category><![CDATA[psychological theories]]></category> <category><![CDATA[rebecca saxe]]></category> <category><![CDATA[scan data]]></category> <category><![CDATA[scientific discipline]]></category> <category><![CDATA[theories of the mind]]></category> <category><![CDATA[theory of the mind]]></category><guid isPermaLink="false">http://brainblogger.com/2008/03/19/functional-mri-a-radiological-window-into-the-mind-part-1/</guid> <description><![CDATA[Functional MRI (fMRI) is one of the most widely used experimental tools in neuroscience today, which allows us to study blood flow patterns to different parts of the brain during a given task. For example during solving mathematical problems, a typical fMRI pattern is seen. Recently however, psychological theories are being tested, and a broader [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/neuroscience-and-neurology-brain-blogger.jpg" alt="Neuroscience_Neurology.jpg" title="Neuroscience_Neurology.jpg" class="left" width="290" height="200" />Functional MRI (fMRI) is one of the most widely used experimental tools in neuroscience today, which allows us to study blood flow patterns to different parts of the brain during a given task. For example during solving mathematical problems, a typical fMRI pattern is seen. Recently however, psychological theories are being tested, and a broader picture of how the mind works is emerging.</p><p>One of the criticisms traditionally faced by psychology as a scientific discipline is the lack of objective data, to back up theories of the mind. For instance, proving the &#8220;existence&#8221; of the subconscious mind is difficult, although intuitively, the model is widely accepted.</p><p>A recent study (1) published on the subject of how knowledge is organized in our mind shows how powerful functional MRI scanning can be, as a tool to prove or disprove psychological theories. It has long been debated whether the human brain perceives living beings as a separate category than the non-living objects (concept domain), or whether, after taking into account the various features like shape, movement, and color (feature domain), it then decides whether it is living or not amongst other attributes. As several objects were presented to a group of 21 participants, detailed fMRI studies were performed of the degree of activation of different parts of the brain, while a yes/no questionnaire designed to test their understanding of concepts versus features was simultaneously analyzed. The results showed with a high degree of statistical significance that human brains organize concepts according to descriptive linguistic features, with the majority using the dominant left half of the brain, and not according to pre-existing conceptual domains of broad categories.</p><p>The issue of whether a picture of a &#8220;standard&#8221; brain from brain scan data can lead us to a &#8220;Theory of the Mind&#8221; was discussed by Harvard neuroscientist Rebecca Saxe in her paper <em>Why and how to study Theory of Mind with fMRI</em>. (2) Central to our radiological window in to the human mind is the concept of &#8220;Regions of Interest&#8221; or ROI, which does not presuppose that distinct areas of the human brain have specific &#8220;thinking&#8221; roles. Rather, a distinct mental activity sets off a pattern of brain activity that involve many areas on the cortex that are close by, or separated widely. In Saxe&#8217;s own research she found that while experimental subjects were reading different kinds of stories &#8212; appearance, bodily sensations, or thoughts &#8212; blood flow patterns on fMRI were distinctly different for the genre of the story, but this difference in patterns were consistent across all the subjects. What fMRI has therefore provided for us is the insight that the number of patterns of activation for different tasks is limitless, but broad patterns do exist. The bigger picture will only emerge after a lot of studies comparing sets of ROI from different experiments are pooled together, providing a clearer picture of how the mind functions through a dynamic, constantly changing network of regions across the brain.</p><p><strong>References</strong></p><p>1. <span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=MARQUES&#038;rft.aufirst=J&#038;rft.au=J+ MARQUES&#038;rft.au=N+CANESSA&#038;rft.au=S+SIRI&#038;rft.au=E+CATRICALA&#038;rft.au=S+CAPPA&#038;rft.title=Brain+Research&#038;rft.atitle=Conceptual+knowledge+in+the+brain%3A+fMRI+evidence+for+a+featural+organization&#038;rft.date=2008&#038;rft.volume=1194&#038;rft.issue=&#038;rft.spage=90&#038;rft.epage=99&#038;rft.genre=article&#038;rft.id=info:DOI/10.1016%2Fj.brainres.2007.11.070"></span>MARQUES, J., CANESSA, N., SIRI, S., CATRICALA, E., CAPPA, S. (2008). Conceptual knowledge in the brain: fMRI evidence for a featural organization. <span style="font-style: italic;">Brain Research, 1194</span>, 90-99. DOI: <a rev="review" href="http://dx.doi.org/10.1016/j.brainres.2007.11.070">10.1016/j.brainres.2007.11.070</a></p><p>2. <span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=SAXE&#038;rft.aufirst=R&#038;rft.au=R+ SAXE&#038;rft.title=Brain+Research&#038;rft.atitle=Why+and+how+to+study+Theory+of+Mind+with+fMRI&#038;rft.date=2006&#038;rft.volume=1079&#038;rft.issue=1&#038;rft.spage=57&#038;rft.epage=65&#038;rft.genre=article&#038;rft.id=info:DOI/10.1016%2Fj.brainres.2006.01.001"></span>SAXE, R. (2006). Why and how to study Theory of Mind with fMRI. <span style="font-style: italic;">Brain Research, 1079</span>(1), 57-65. DOI: <a rev="review" href="http://dx.doi.org/10.1016/j.brainres.2006.01.001">10.1016/j.brainres.2006.01.001</a></p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/03/19/functional-mri-a-radiological-window-into-the-mind-part-1/feed/</wfw:commentRss> <slash:comments>3</slash:comments> </item> <item><title>Follow the Leader &#8211; Insight into Human Decision Making</title><link>http://brainblogger.com/2008/03/08/follow-the-leader-insight-into-human-decision-making/</link> <comments>http://brainblogger.com/2008/03/08/follow-the-leader-insight-into-human-decision-making/#comments</comments> <pubDate>Sat, 08 Mar 2008 13:31:09 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Psychiatry & Psychology]]></category> <category><![CDATA[behavioral ecologist]]></category> <category><![CDATA[biological sciences]]></category> <category><![CDATA[brethren]]></category> <category><![CDATA[consensus decision]]></category> <category><![CDATA[crowd of people]]></category> <category><![CDATA[crowd size]]></category> <category><![CDATA[decision makers]]></category> <category><![CDATA[decisive influence]]></category> <category><![CDATA[emergency planning]]></category> <category><![CDATA[fashion fads]]></category> <category><![CDATA[flocks]]></category> <category><![CDATA[follower]]></category> <category><![CDATA[human decision]]></category> <category><![CDATA[john dyer]]></category> <category><![CDATA[large crowds]]></category> <category><![CDATA[leeds university]]></category> <category><![CDATA[parallels]]></category> <category><![CDATA[pedestrian flow]]></category> <category><![CDATA[planning strategies]]></category> <category><![CDATA[university england]]></category><guid isPermaLink="false">http://brainblogger.com/2008/03/08/follow-the-leader-insight-into-human-decision-making/</guid> <description><![CDATA[Scientists at Leeds University, England believe that they have found the answer to how a lot of our unconscious actions are generated &#8212; by simply following our herd of brethren! A new study demonstrates that it only takes about 5% of people to have a decisive influence on the direction that a crowd of people would [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/psychiatry-and-psychology-brain-blogger.jpg" alt="Psychiatry_Psychology2.jpg" title="Psychiatry_Psychology2.jpg" class="left" width="290" height="200" />Scientists at Leeds University, England believe that they have found the answer to how a lot of our unconscious actions are generated &#8212; by simply following our herd of brethren!</p><p>A new study demonstrates that it only takes about 5% of people to have a decisive influence on the direction that a crowd of people would take, and the rest simply follow. Prof. Jens Krause a behavioral ecologist, with PhD student John Dyer, designed a series of experiments at Leeds where groups of people were asked to walk around randomly in a large hall. Within the group, a selected few participants received more detailed instructions about how and where to walk. Participants were not allowed to communicate with any another person but had to stay within an arms length of each other.</p><p>The study showed these &#8220;snake-like patterns&#8221; people unconsciously adopted, as they began following others without being unaware that they were doing so. In a way, they had adopted a consensus decision, but being totally unaware of it. The study used different crowd sizes to assess the leader-to-follower ratios at each level, and it soon emerged that the bigger the crowd size, the smaller the number of decision makers required. In large crowds of 200 or more, 5% of the group was enough to influence the direction in which it traveled!</p><p>&#8220;There are many situations where this information could be used to good effect,&#8221; Prof. Krause of the University&#8217;s Faculty of Biological Sciences stated in a recent interview. &#8220;At one extreme, it could be used to inform emergency planning strategies and at the other, it could be useful in organizing pedestrian flow in busy areas.&#8221;</p><p>According to Prof. Krause, the study started as part of studying animal grouping behaviour, and as it convincingly demonstrates, there are strong parallels between human crowds and animal flocks, which might be instinctual.</p><p>But on a metaphorical plane, does this study explain phenomena like fashion fads and opinion shifts too?</p><p><strong>Reference</strong></p><p><span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=DYER&#038;rft.aufirst=J&#038;rft.au=J+ DYER&#038;rft.au=C+IOANNOU&#038;rft.au=L+MORRELL&#038;rft.au=D+CROFT&#038;rft.au=I+COUZIN&#038;rft.au=D+WATERS&#038;rft.au=J+KRAUSE&#038;rft.title=Animal+Behaviour&#038;rft.atitle=Consensus+decision+making+in+human+crowds&#038;rft.date=2007&#038;rft.volume=&#038;rft.issue=&#038;rft.spage=&#038;rft.genre=article&#038;rft.id=info:DOI/10.1016%2Fj.anbehav.2007.05.010"></span>DYER, J., IOANNOU, C., MORRELL, L., CROFT, D., COUZIN, I., WATERS, D., KRAUSE, J. (2007). Consensus decision making in human crowds. <em>Animal Behaviour</em>,75(2), 461-470. DOI: <a rev="review" href="http://dx.doi.org/10.1016/j.anbehav.2007.05.010">10.1016/j.anbehav.2007.05.010</a></p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/03/08/follow-the-leader-insight-into-human-decision-making/feed/</wfw:commentRss> <slash:comments>2</slash:comments> </item> <item><title>Is it the Brain or the Game? Gender Differences in Gaming</title><link>http://brainblogger.com/2008/03/06/is-it-the-brain-or-the-game/</link> <comments>http://brainblogger.com/2008/03/06/is-it-the-brain-or-the-game/#comments</comments> <pubDate>Thu, 06 Mar 2008 18:06:20 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Neuroscience & Neurology]]></category> <category><![CDATA[computer version]]></category> <category><![CDATA[computer video games]]></category> <category><![CDATA[conundrum]]></category> <category><![CDATA[gaming behavior]]></category> <category><![CDATA[gender difference]]></category> <category><![CDATA[gender differences]]></category> <category><![CDATA[generalizations]]></category> <category><![CDATA[male brain]]></category> <category><![CDATA[meso]]></category> <category><![CDATA[mri imaging]]></category> <category><![CDATA[neural processes]]></category> <category><![CDATA[old chicken]]></category> <category><![CDATA[playing video games]]></category> <category><![CDATA[psychiatric research]]></category> <category><![CDATA[research findings]]></category> <category><![CDATA[reward center]]></category> <category><![CDATA[simplified computer]]></category> <category><![CDATA[stanford university]]></category> <category><![CDATA[video gaming industry]]></category> <category><![CDATA[widows]]></category><guid isPermaLink="false">http://brainblogger.com/2008/03/06/is-it-the-brain-or-the-game/</guid> <description><![CDATA[New research findings from the Stanford University proves that men find playing video games more rewarding. This wouldn&#8217;t appear surprising to the millions of console and PC gaming widows worldwide, but this gives us an opportunity to have a look at the good old chicken-and-egg conundrum in the context of arriving at sweeping generalizations on [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/neuroscience-and-neurology-brain-blogger.jpg" alt="Neuroscience_Neurology.jpg" title="Neuroscience_Neurology.jpg" class="left" width="290" height="200" />New research findings from the Stanford University <em>proves</em> that men find playing video games more rewarding. This wouldn&#8217;t appear surprising to the millions of console and PC gaming widows worldwide, but this gives us an opportunity to have a look at the good old <em>chicken-and-egg</em> conundrum in the context of arriving at sweeping generalizations on gender difference issues on the basis of imaging alone.</p><p>The abstract of the study (1) recently published in <em>Psychiatric Research</em> begins with the statement &#8220;Little is known about the underlying neural processes of playing computer/video games, despite the high prevalence of its gaming behavior, especially in males.&#8221; The study carried out on 11 men and women, on a &#8220;simplified&#8221; computer version of a game involving clicking on balls moving away from the centre of the screen in an attempt to gain &#8220;territory&#8221; on the screen, which was the object of winning. It concluded that men were more motivated to win territory, and therefore performed better despite the fact that both groups perfectly understood the objective of the game. (2) Functional MRI imaging performed at the time showed that the men&#8217;s meso-cortico-limbic centers, traditionally considered the brain&#8217;s &#8220;reward center&#8221; were more activated as they were winning. The authors concluded that territorial dominance is hardwired in the male brain, which is why men enjoy playing and winning computer games more than women.</p><p>While the study and its conclusions have a lyrical simplicity to it, observations from the real world contradict the hypothesis. Data from the ESA (3), dedicated to research of the trends in the video gaming industry, reveal the steady increase in the number of women gamers over the years. Currently, 38% of American videogame players and 48% of gaming parents are women. Gaming for women is not always about winning &#8212; consider the fact that 70% of the players of <em>Sims</em>, considered by some to be the most successful game ever are women; the game focuses on the intricacies of relationships and urban life. (4) Two recent reports are also worth mentioning &#8211; first, a recent report from the Australian gaming industry (5) that women are the fastest growing market segment along with old adults in a rapidly changing gaming demography. In Japan, in what has been described as a &#8220;seismic shift&#8221; (6), women gamers have actually overtaken their male counterparts with newer consoles like the Wii and DS, both from Nintendo. Lifestyle games on cookery, personal grooming and simulated sports are at the heart of the boom.</p><p>Reconciling the Stanford study and industry statistics is not easy: I suppose that the design of any psychosocial experiment largely determines its outcome under its unique circumstances, but is not necessarily applicable to real life. If we take video gaming out of its narrow context of two teenage geeks furiously clawing their consoles in a death match to outbid each other, to its broader modern context, I do think that the problem why men have &#8220;traditionally&#8221; found video games more rewarding, lies in the games themselves which have focused on competition and visuospatial skills.</p><p>But there are many ways of firing our meso-cortico-limbic centers when it comes to video gaming &#8212; it depends mostly on the games we choose as well as what the industry is designing for us.</p><p><strong>References</strong></p><p>1. <span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=HOEFT&#038;rft.aufirst=F&#038;rft.au=F+ HOEFT&#038;rft.au=C+WATSON&#038;rft.au=S+KESLER&#038;rft.au=K+BETTINGER&#038;rft.au=A+REISS&#038;rft.title=Journal+of+Psychiatric+Research&#038;rft.atitle=Gender+differences+in+the+mesocorticolimbic+system+during+computer+game-play&#038;rft.date=2008&#038;rft.volume=42&#038;rft.issue=4&#038;rft.spage=253&#038;rft.epage=258&#038;rft.genre=article&#038;rft.id=info:DOI/10.1016%2Fj.jpsychires.2007.11.010"></span>HOEFT, F., WATSON, C., KESLER, S., BETTINGER, K., REISS, A. (2008). Gender differences in the mesocorticolimbic system during computer game-play. <span style="font-style: italic;">Journal of Psychiatric Research, 42</span>(4), 253-258. DOI: <a rev="review" href="http://dx.doi.org/10.1016/j.jpsychires.2007.11.010">10.1016/j.jpsychires.2007.11.010</a></p><p>2. <a href="http://med.stanford.edu/news_releases/2008/february/videobrain.html">Video games activate reward regions of brain in men more than women, Stanford study finds</a>. <em>Stanford School of Medicine &#8211; News Release</em>. 2008.</p><p>3. <a href="http://www.theesa.com">The Entertainment Software Association</a></p><p>4. Darren Waters. <a href="http://news.bbc.co.uk/1/hi/technology/5271852.stm">Games industry is &#8216;failing women&#8217;</a>. <em>BBC News</em>. 2008.</p><p>5. <a href="http://www.smh.com.au/news/articles/gaming-on-the-rise/2007/12/19/1197740282479.html">Gaming on the rise</a>. <em>The Sydney Morning Herald</em>. 2008.</p><p>6. Leo Lewis. <a href="http://business.timesonline.co.uk/tol/business/markets/japan/article2629649.ece">Nintendo&#8217;s women gamers could transform market</a>. Times Online. 2008.</p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/03/06/is-it-the-brain-or-the-game/feed/</wfw:commentRss> <slash:comments>2</slash:comments> </item> <item><title>Why Some Men, Like Women, Cannot Read Maps Too</title><link>http://brainblogger.com/2008/03/01/why-some-men-like-women-cannot-read-maps-too/</link> <comments>http://brainblogger.com/2008/03/01/why-some-men-like-women-cannot-read-maps-too/#comments</comments> <pubDate>Sat, 01 Mar 2008 13:14:46 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Anti Stigmatization]]></category> <category><![CDATA[allan pease]]></category> <category><![CDATA[aviation technology]]></category> <category><![CDATA[biological basis]]></category> <category><![CDATA[combat aviation]]></category> <category><![CDATA[computer simulation study]]></category> <category><![CDATA[fighter pilots]]></category> <category><![CDATA[gay men]]></category> <category><![CDATA[gender differences]]></category> <category><![CDATA[human brains]]></category> <category><![CDATA[laboratory conditions]]></category> <category><![CDATA[male brain]]></category> <category><![CDATA[nature nurture]]></category> <category><![CDATA[navigational abilities]]></category> <category><![CDATA[queen mary hospital]]></category> <category><![CDATA[role models]]></category> <category><![CDATA[straight men]]></category> <category><![CDATA[straight women]]></category> <category><![CDATA[sumo wrestlers]]></category> <category><![CDATA[university of london]]></category> <category><![CDATA[women in the 20th century]]></category><guid isPermaLink="false">http://brainblogger.com/2008/03/01/why-some-men-like-women-cannot-read-maps-too/</guid> <description><![CDATA[I never quite got around to write the sequel to Barbara and Allan Pease&#8217;s evocative work (1), although I had figured out a nice name for it, &#8220;Why men don&#8217;t use makeup, and women can&#8217;t Sumo wrestle.&#8221; Not to make fun of the genetic determinists who study gender differences, but to drive home the whole [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/anti-stigmatization-brain-blogger.jpg" alt="Anti_Stigmatization2.jpg" title="Anti_Stigmatization2.jpg" class="left" width="290" height="200" />I never quite got around to write the sequel to Barbara and Allan Pease&#8217;s evocative work (1), although I had figured out a nice name for it, &#8220;Why men don&#8217;t use makeup, and women can&#8217;t Sumo wrestle.&#8221; Not to make fun of the genetic determinists who study gender differences, but to drive home the whole nature-nurture point on this issue: men and women have evolved to be different. But not in its restricted Darwinian sense, but in the current expanded evolutionary contexts as well &#8212; social, psychological and politico-economic.</p><p>However, as I have closely followed the sexual dimorphism debate over the years, I am of the opinion that although there is irrefutable scientific evidence that there are important differences in the way male and human brains function, they are not significant enough to justify any role stereotyping in humans on a purely biological basis. Women can become Sumo wrestlers if they wanted to and they do these days; in fact Japan held its first-ever official women&#8217;s Sumo wrestling championship in 1997 breaking away with the age-old tradition of keeping women away from the arena, even as spectators. Women in the 20th century have been fairly successful as &#8220;father role models,&#8221; despite significant opposition to the idea from orthodox quarters.</p><p>Recent behavioral research has focussed on the gay male brain, and one such recent study (2) from the Queen Mary Hospital, University of London has reported that when it comes to spatial navigational abilities, gay men&#8217;s performance tend to equal that of women, which <em>under laboratory conditions</em>, is worse compared to straight men. In the computer-simulation study carried out on 140 volunteers, gay men, straight women and lesbians shared the same weaknesses when it came to tasks that required spatial navigational abilities. I can accept that as a possible explanation why there are so few women who aspire to be fighter pilots, while arguing of course that current combat aviation technology is still not quite as gender-neutral as one can hope for. But in the above case, the reaction of the British press all across the UK to this research finding was simply hilarious.</p><p>For example <em>The Telegraph</em>, a national daily ran its story &#8220;<a href="http://www.telegraph.co.uk/news/main.jhtml;jsessionid=IWHVYNEWVM1LJQFIQMFSFF4AVCBQ0IV0?xml=/news/2008/01/03/ngay103.xml">Women and gay men are worst drivers</a>,&#8221; without justifying their assertion. Worse, an accompanying picture was captioned, &#8220;Be afraid: gay men or women could be behind the wheel of any car.&#8221; Despite the fact that in Britain women are universally acknowledged as safer drivers, and pay less insurance than men (indeed in my household, both our cars are insured in my wife&#8217;s name, quite legally of course). Here is a classic demonstration of the pitfalls of illogical stereotyping through misinterpretation of research findings &#8212; life skills in modern human society are too complex to be evaluated on the basis of laboratory tests of simple behavioral tests alone. Dr. Rahman, the senior author <a href="http://network.nature.com/london/news/Q&amp;A/2008/01/11/of-sexual-and-spatial-orientations">agrees</a> that &#8220;the headlines splashed across the British press about driving were completely taken out of context.&#8221;</p><p>Behavioral psychology is valuable in numerous aspects, but we must be cautious about jumping to conclusions. And I have always acknowledged that at least in my family, my wife is the better driver.</p><p><strong>References</strong></p><p>1. <em>Why Men Don&#8217;t Listen And Women Can&#8217;t Read Maps: How We&#8217;re Different and What To Do About It: How We&#8217;re Different and What to Do About It</em>. Barbara and Allan Pease. Orion. March 2001.</p><p>2. <span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=Rahman&#038;rft.aufirst=Qazi&#038;rft.au=Qazi+ Rahman&#038;rft.au=Johanna+Koerting&#038;rft.title=Hippocampus&#038;rft.atitle=Sexual+orientation-related+differences+in+allocentric+spatial+memory+tasks&#038;rft.date=2007&#038;rft.volume=18&#038;rft.issue=1&#038;rft.spage=55&#038;rft.epage=63&#038;rft.genre=article&#038;rft.id=info:DOI/10.1002%2Fhipo.20375"></span>Rahman, Q., Koerting, J. (2007). Sexual orientation-related differences in allocentric spatial memory tasks. <span style="font-style: italic;">Hippocampus, 18</span>(1), 55-63. DOI: <a rev="review" href="http://dx.doi.org/10.1002/hipo.20375">10.1002/hipo.20375</a></p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/03/01/why-some-men-like-women-cannot-read-maps-too/feed/</wfw:commentRss> <slash:comments>1</slash:comments> </item> <item><title>The Chattering Brain &#8211; How Chronic Pain Throws our Cortex out of Sync</title><link>http://brainblogger.com/2008/02/26/the-chattering-brain-how-chronic-pain-throws-our-cortex-out-of-sync/</link> <comments>http://brainblogger.com/2008/02/26/the-chattering-brain-how-chronic-pain-throws-our-cortex-out-of-sync/#comments</comments> <pubDate>Tue, 26 Feb 2008 15:15:06 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Neuroscience & Neurology]]></category> <category><![CDATA[areas of the brain]]></category> <category><![CDATA[associate research professor]]></category> <category><![CDATA[brain activation patterns]]></category> <category><![CDATA[brain functions]]></category> <category><![CDATA[cerebral cortex]]></category> <category><![CDATA[chronic depression]]></category> <category><![CDATA[chronic low back pain]]></category> <category><![CDATA[chronic pain sufferers]]></category> <category><![CDATA[computer screens]]></category> <category><![CDATA[control group]]></category> <category><![CDATA[feinberg school of medicine]]></category> <category><![CDATA[fmri]]></category> <category><![CDATA[interconnection]]></category> <category><![CDATA[irreversible damage]]></category> <category><![CDATA[low back pain]]></category> <category><![CDATA[neurological abnormalities]]></category> <category><![CDATA[neurons]]></category> <category><![CDATA[northwestern university]]></category> <category><![CDATA[relevant areas]]></category> <category><![CDATA[school of medicine]]></category><guid isPermaLink="false">http://brainblogger.com/2008/02/26/the-chattering-brain-how-chronic-pain-throws-our-cortex-out-of-sync/</guid> <description><![CDATA[A new study from the Northwestern University&#8217;s Feinberg School of Medicine has provided important clues to how chronic pain might throw our lives out of gear by affecting many areas of the cerebral cortex. Worse, if left unchecked, it could lead to irreversible damage to the interconnection between the neurons, leading to permanent changes in [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/neuroscience-and-neurology-brain-blogger.jpg" alt="Neuroscience_Neurology2.jpg" title="Neuroscience_Neurology2.jpg" class="left" width="290" height="200" />A new study from the Northwestern University&#8217;s Feinberg School of Medicine has provided important clues to how chronic pain might throw our lives out of gear by affecting many areas of the cerebral cortex. Worse, if left unchecked, it could lead to irreversible damage to the interconnection between the neurons, leading to permanent changes in the way our brain functions.</p><p>Using functional MRI (fMRI) scanning, Dante Chialvo, lead author and associate research professor of physiology at the Feinberg School, compared the brain activation patterns of people with chronic low back pain to a group of pain-free volunteers while both groups were visually tracking a moving object on computer screens. The study showed that although the pain sufferers performed the task well,  they were using their brain in a very different way compared to the normal control group.</p><p>With normal brains, when the subject concentrated on one task, like visual tracking, only a few areas of the brain were activated, while the other areas were &#8217;silent&#8217; from a neurological point of view. This is a state of equilibrium, known as the resting state of the brain, as the different areas of the brain co-operate to give &#8216;rest&#8217; to each other, while only a few relevant areas are active.</p><p>In contrast in the brains of the group with chronic pain, this co-operative resting state was typically absent, and the neurons kept on firing indefinitely without periods of rest. Dr Chialvo&#8217;s work suggests that in chronic pain, this continued firing prevents normal interneuronal connections and damages the brain, causing functional alterations. He hypothesizes that this overactive brain firing in chronic pain sufferers could affect their mood, producing chronic depression and a host of other neurological abnormalities seen with chronic pain. In the future in chronic pain sufferers, simply treating pain might be inadequate, as this study implies. Chronic pain may be much more of  a whole-brained phenomenon than we once thought.</p><p><strong>Reference</strong></p><p><span class="Z3988" title="ctx_ver=Z39.88-2004&#038;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&#038;rft.aulast=Baliki&#038;rft.aufirst=M&#038;rft.aumiddle=N&#038;rft.au=M+ Baliki&#038;rft.au=P+Y+Geha&#038;rft.au=A+V+Apkarian&#038;rft.au=D+R+Chialvo&#038;rft.title=Journal+of+Neuroscience&#038;rft.atitle=Beyond+Feeling%3A+Chronic+Pain+Hurts+the+Brain%2C+Disrupting+the+Default-Mode+Network+Dynamics&#038;rft.date=2008&#038;rft.volume=28&#038;rft.issue=6&#038;rft.spage=1398&#038;rft.epage=1403&#038;rft.genre=article&#038;rft.id=info:DOI/10.1523%2FJNEUROSCI.4123-07.2008"></span>Baliki, M.N., Geha, P.Y., Apkarian, A.V., Chialvo, D.R. (2008). Beyond Feeling: Chronic Pain Hurts the Brain, Disrupting the Default-Mode Network Dynamics. <span style="font-style: italic;">Journal of Neuroscience, 28</span>(6), 1398-1403. DOI: <a rev="review" href="http://dx.doi.org/10.1523/JNEUROSCI.4123-07.2008">10.1523/JNEUROSCI.4123-07.2008</a></p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/02/26/the-chattering-brain-how-chronic-pain-throws-our-cortex-out-of-sync/feed/</wfw:commentRss> <slash:comments>2</slash:comments> </item> <item><title>Extinction Fears of the Red-Headed Homo Sapien</title><link>http://brainblogger.com/2008/02/17/extinction-fears-of-the-red-headed-homo-sapien/</link> <comments>http://brainblogger.com/2008/02/17/extinction-fears-of-the-red-headed-homo-sapien/#comments</comments> <pubDate>Sun, 17 Feb 2008 15:02:59 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Articles & Studies]]></category> <category><![CDATA[ann arbor michigan]]></category> <category><![CDATA[extinction]]></category> <category><![CDATA[homo sapien]]></category> <category><![CDATA[intermarriage]]></category> <category><![CDATA[mc1r]]></category> <category><![CDATA[multicultural populations]]></category> <category><![CDATA[mutation]]></category> <category><![CDATA[northern europe]]></category> <category><![CDATA[passions]]></category> <category><![CDATA[phenotype]]></category> <category><![CDATA[receptor gene]]></category> <category><![CDATA[recessive gene]]></category> <category><![CDATA[recessive genes]]></category> <category><![CDATA[recessive trait]]></category> <category><![CDATA[red hair]]></category> <category><![CDATA[redheads]]></category> <category><![CDATA[several thousand]]></category> <category><![CDATA[social networking site]]></category> <category><![CDATA[steve warrington]]></category> <category><![CDATA[vitamin d]]></category><guid isPermaLink="false">http://brainblogger.com/2008/02/17/extinction-fears-of-the-red-headed-homo-sapien/</guid> <description><![CDATA[About 4% of the world&#8217;s population possess the recessive gene for red hair, and actually 2% are redheads, as a result of a mutation that arose in Northern Europe several thousand years ago. Scientists have been divided in their opinion about whether the red headed population is headed for extinction in an age of global [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/articles-and-studies-brain-blogger.jpg" alt="Articles_Studies.jpg" title="Articles_Studies.jpg" class="left" width="290" height="200" />About 4% of the world&#8217;s population possess the recessive gene for red hair, and actually 2% are redheads, as a result of a mutation that arose in Northern Europe several thousand years ago. Scientists have been divided in their opinion about whether the red headed population is headed for extinction in an age of global mingling.</p><p>Jacob Silverman reported his findings in <a href="http://science.howstuffworks.com/redhead-extinction.htm">Are redheads going extinct</a>:</p><blockquote><p>Red hair is caused by a mutation in the MC1R (melanocortine 1 receptor gene)&#8230; Because it&#8217;s a recessive trait, red hair can easily skip a generation. It can then reappear after skipping one or more generations if both parents, no matter their hair color, carry the red hair gene.</p></blockquote><p>That is a slightly reassuring view, as it implies, that the gene will stay in the population. But most genes are clustered in certain populations, and intermarriage in communities ensures that the prevalence of recessive genes do not get diluted. But with increasingly multicultural populations in the West, where red hair genes are mostly concentrated, some scientists are afraid, redheads as a phenotype could become extinct within a 100 years.</p><p>Leading the redhead preservation brigade is the social networking site <a href="http://redhedd.com">Redhedd.com</a>, which insists on dating and breeding amongst redheads exclusively, to preserve mankind&#8217;s red heritage. It is aggressive in its stance, compared to more moderate devoted sites like Redhead Passions and Realm of the Redheads, and proclaims in its manifesto that its primary object is to &#8220;save the redheads.&#8221;</p><p>&#8220;In order to save redheads we have to mingle redheads with redheads, to concentrate the two genes that make red hair&#8221;, instructs the site founder in 2007 &#8212; Steve Warrington of Ann Arbor, Michigan.</p><p>Last August, <em>National Geographic</em> ran the story where &#8220;ginger&#8221; was predicted to be extinct in a 100 years or so. The gene initially had a positive survival effect by increasing the body&#8217;s ability to synthesize Vitamin D in the presence of sunlight, particularly in the northernmost latitudes with relatively less sunlight. But in the era of dietary fortification, it has lost its usefulness, and even makes carriers more prone to cancer and heat and cold-related pain.</p><p>But for those red head preservationists not to be put off by such trivial counterarguments, statistically the best place to preserve their heritage is Scotland, where apparently 40% of the population carry the gene and 13% actually have red hair.</p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/02/17/extinction-fears-of-the-red-headed-homo-sapien/feed/</wfw:commentRss> <slash:comments>3</slash:comments> </item> <item><title>One Up for the Spanish &#8220;Siesta&#8221;</title><link>http://brainblogger.com/2008/02/09/one-up-for-the-spanish-siesta/</link> <comments>http://brainblogger.com/2008/02/09/one-up-for-the-spanish-siesta/#comments</comments> <pubDate>Sat, 09 Feb 2008 14:26:05 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[Neuroscience & Neurology]]></category> <category><![CDATA[afternoon]]></category> <category><![CDATA[long-term memory]]></category> <category><![CDATA[memory]]></category> <category><![CDATA[nap]]></category> <category><![CDATA[naps]]></category> <category><![CDATA[performance]]></category> <category><![CDATA[research]]></category> <category><![CDATA[Siesta]]></category> <category><![CDATA[sleep]]></category> <category><![CDATA[studies]]></category> <category><![CDATA[study]]></category><guid isPermaLink="false">http://brainblogger.com/2008/02/09/one-up-for-the-spanish-siesta/</guid> <description><![CDATA[Good news from the world of medicine for those caught snoozing after lunch at their desks &#8212; you can claim it was a deliberate memory enhancement strategy. New research from the University of Haifa&#8217;s Center for Brain and Behavior Research shows that a 90-minute day nap speeds up the process of long-term memory consolidation as [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/neuroscience-and-neurology-brain-blogger.jpg" alt="Neuroscience_Neurology.jpg" title="Neuroscience_Neurology.jpg" class="left" width="290" height="200" />Good news from the world of medicine for those caught snoozing after lunch at their desks &#8212; you can claim it was a deliberate memory enhancement strategy. New research from the University of Haifa&#8217;s Center for Brain and Behavior Research shows that a 90-minute day nap speeds up the process of long-term memory consolidation as well as improve learned performance.</p><p>The findings of Dr. Maria Korman, Professor Avi Karni and their team were published recently in the journal <em>Nature Neuroscence</em>, based on a study of two groups of volunteers who were given a task that involved bringing together their thumb and finger repeatedly in a sequence. One group was allowed to take a 90 minutes afternoon nap after learning the task while the other group stayed awake. The group which took the afternoon nap showed a distinct improvement in its performance, compared to the other. By comparison, sleeping at night produced the same skill levels in both groups, demonstrating the improvement  was causally related to the daytime nap only.</p><p>In another crucial part of the experiment, the role of a &#8220;siesta&#8221; was investigated in learning two tasks in sequence, with a gap of a few hours. Normally, learning a new task shortly after another one produces &#8216;interference&#8217;, by which the first task is often forgotten due to the effects of the second, as the former task&#8217;s memory has not had a chance to become &#8220;consolidated.&#8221; However, in the above experiment, a 90-minute daytime nap after learning the first task in a sub-group of volunteers produced significantly less &#8220;interference,&#8221; indicating that a short period of nap dramatically improved long-term memory consolidation of the first task.</p><p>Although the exact mechanism by which a short period of nap accelerates the memory consolidation of the learning process is unknown, the relationship between sleep and memory consolidation has been the focus of scientific study for quite some time. Day napping might be a good strategy to utilize in work situations where learning is involved, but some cultures know that already.</p><p>In Spain and Latin America, the &#8220;siesta&#8221; has been a tradition for many centuries &#8212; shops and establishments close for several hours, and after a refreshing afternoon sleep, resume their afternoon and evening business, feeling invigorated. Some Japanese offices have napping rooms where mid-day lunch-time sleep can be taken, and the Washington Post <a href="http://www.washingtonpost.com/wp-dyn/content/article/2007/02/12/AR2007021200626.html">reported</a> on February 13, 2007 about studies in Greece that indicate that daytime napping reduces the risk of heart disease, something which has been a tradition there.</p><p><strong>Reference</strong></p><p>Korman M, Doyon J, Doljansky J, Carrier J, Dagan Y, Karni A. <a href="http://www.nature.com/neuro/journal/v10/n9/abs/nn1959.html">Daytime sleep condenses the time course of motor memory consolidation</a>. Nat Neurosci. 2007 Sep;10(9):1085-6.</p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/02/09/one-up-for-the-spanish-siesta/feed/</wfw:commentRss> <slash:comments>1</slash:comments> </item> <item><title>Can You Teach the Pursuit of Happiness Online?</title><link>http://brainblogger.com/2008/02/06/can-you-teach-the-pursuit-of-happiness-online/</link> <comments>http://brainblogger.com/2008/02/06/can-you-teach-the-pursuit-of-happiness-online/#comments</comments> <pubDate>Wed, 06 Feb 2008 16:01:53 +0000</pubDate> <dc:creator>Sudip Ghosh, MD</dc:creator> <category><![CDATA[BioPsychoSocial Health]]></category> <category><![CDATA[brain activation]]></category> <category><![CDATA[cerebral cortices]]></category> <category><![CDATA[distance education]]></category> <category><![CDATA[evolutionary tree]]></category> <category><![CDATA[happiness]]></category> <category><![CDATA[harvard university]]></category> <category><![CDATA[introductory economics]]></category> <category><![CDATA[limbic system]]></category> <category><![CDATA[marty seligman]]></category> <category><![CDATA[neural activity]]></category> <category><![CDATA[online course]]></category> <category><![CDATA[pennsylvania professor]]></category> <category><![CDATA[personal transformation]]></category> <category><![CDATA[pleasure]]></category> <category><![CDATA[pleasure centers]]></category> <category><![CDATA[positive feelings]]></category> <category><![CDATA[positive psychology]]></category> <category><![CDATA[psychological basis]]></category> <category><![CDATA[psychology]]></category> <category><![CDATA[pursuit of happiness]]></category> <category><![CDATA[semantic ramifications]]></category> <category><![CDATA[shahar]]></category> <category><![CDATA[social psychologist]]></category> <category><![CDATA[state of happiness]]></category> <category><![CDATA[universal basis]]></category> <category><![CDATA[william mcdougall]]></category><guid isPermaLink="false">http://brainblogger.com/2008/02/06/can-you-teach-the-pursuit-of-happiness-online/</guid> <description><![CDATA[William McDougall, Harvard social psychologist, wrote that people can be happy while in pain and unhappy while experiencing pleasure. While the philosophical and semantic ramifications of the term &#8220;happiness&#8221; are still far away from being well-defined on a universal basis, it is generally accepted that while short-term happiness are more to do with positive feelings [...]]]></description> <content:encoded><![CDATA[<p><img src="http://brainblogger.com/images/biopsychosocial-health-brain-blogger.jpg" alt="BioPsychoSocial_Health2.jpg" title="BioPsychoSocial_Health2.jpg" class="left" width="290" height="200" />William McDougall, Harvard social psychologist, wrote that people can be happy while in pain and unhappy while experiencing pleasure. While the philosophical and semantic ramifications of the term &#8220;happiness&#8221; are still far away from being well-defined on a universal basis, it is generally accepted that while short-term happiness are more to do with positive feelings like pleasure or victory, long-term happiness tends to be more value based and goal-oriented.</p><p>One thing is certain however: on a psychological basis, a state of happiness is popular and sought after, going by the number of university courses that teach exclusively how to be happy as part of our overall well-being. This is an encouraging trend as it indicates that progressively more and more people are eager to realize &#8220;happiness&#8221; through their cerebral cortices (in the brain), rather than through their pleasure centers in the limbic systems. Realizing the need to be happy, rather than being driven by our instincts to be happy is a significant step up the social evolutionary tree.</p><p>The leader of the pack of such courses is Tal D. Ben-Shahar at Harvard University, who reached the limelight a couple of years ago for enrolling the <a href="http://www.boston.com/news/local/articles/2006/03/10/harvards_crowded_course_to_happiness/">most students</a> on  single course at Harvard, 855, beating  even introductory economics. Termed as &#8220;positive psychology,&#8221; such courses pioneered by Marty Seligman, the University of Pennsylvania professor who is considered its father, focus upon optimism as a way of daily living and a route to personal transformation. There is clinical evidence that well-adjusted, &#8220;happy&#8221; people have patterns of brain activation different from the rest, although whether such neural activity can be programmed through &#8220;formal&#8221; teaching is far from clear.</p><p>But from this February, Ben-Shahar is actually teaching the <a href="http://www.extension.harvard.edu/2007-08/courses/22827.jsp?caller=dce">course online</a>, both on a credit  ($1625) or non-credit    ($700) basis. In  his recent <a href="http://www.comedycentral.com/motherload/player.jhtml?ml_video=91293&amp;is_large=true">interview</a> on &#8220;The Daily Show,&#8221; host Jon Stewart joked that he could not believe that anyone could get away with running a course on happiness. But such courses are merely a growing trend, something I find very heartening. Young people are finally willing to <em>formally</em> commit their cerebral cortices  to ask the big questions of life and its meaning.</p><p>I wish you the very best of pre-frontal lobe activity in life.</p> ]]></content:encoded> <wfw:commentRss>http://brainblogger.com/2008/02/06/can-you-teach-the-pursuit-of-happiness-online/feed/</wfw:commentRss> <slash:comments>1</slash:comments> </item> </channel> </rss>
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