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Monthly Archive for November, 2009

Test tubes

Drugs & Clinical Trials

One Size Does Not Fit All

November 30, 2009 | By Jennifer Gibson, PharmD | 3 Comments

Up to half of drug therapy is ineffective, according to recent statistics. This leaves patients’ diseases untreated, but also places them at risk for side effects and drug interactions. The reason for the unpredictability in the effectiveness of medication comes from a variety of factors: individual differences in enzymes that metabolize drugs, variations in drug transporters, ethnic differences, and environmental changes. For decades, the idea of personalized medicine -- assessing and evaluating individual differences to tailor medicine and therapy regimens for the best results -- has brought about new drugs and led to effective treatment of several diseases. However, now clinicians and researchers are returning to old drugs to optimize personalized therapy.

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Plane in flight

Health & Healthcare

The Secret to Good Health – Listen to the Data

November 27, 2009 | By Rachel Danks, PhD | 13 Comments

A recent study proved what we all already know... that healthy living really does improve long-term health. A lot. The US-based study found that not smoking, maintaining a healthy weight (BMI <30), exercising regularly (3.5 hours/week) and eating a balanced diet (high in fruits, vegetables, and whole grains, low in meat) reduced the risk of developing chronic disease by nearly 80% over the course of the study. 80%! Just imagined if a new drug promised an 80% reduction in chronic diseases -- it would be a wonder drug! People would be beating a path to their primary care providers, demanding a prescription. Shareholders in the manufacturers would never have to work again!

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Candy galore

Psychology & Psychiatry

Sugar and Spice and Everything Nice?

November 23, 2009 | By Jennifer Gibson, PharmD | 3 Comments

If we are what we eat, then we might expect children who eat a lot of candy to be sweet and lovable. Quite the opposite, according to recent research. Authors of a study published in a recent issue of the British Journal of Psychiatry claim that children who eat a lot of confectionery treats are more likely to be violent adults.The British researchers followed more than 17,000 British children born in 1970 for almost 4 decades. More than two-thirds (69%) of the children arrested for violent behavior by age 34 ate candy daily at age 10.

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Hospital old

Health & Healthcare

A New Look at Medical Errors in Residency Training

November 18, 2009 | By T. A. McNamee, MD | 4 Comments

It’s a phenomenon that medical educators have long suspected but haven’t been able to prove: a rise in medical errors when newly-hatched physicians begin their residency training programs in July. This suspected occurrence has been studied several times, but until recently, no conclusive evidence existed that it actually was true. For the first time, a study based in Australia has been able to demonstrate that this really does happen, but perhaps not for the reasons you’d suspect.

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