Monthly Archive for March, 2009
Lithium as a Neuroprotectant?
Lithium is an elemental chemical found naturally as an alkali metal. The ionic form can be used to form salts which are readily available for medicinal purposes. Although the exact mechanism of action for lithium is unknown, it is believed to function by simultaneously raising serotonin levels and lowering norepinephrine levels. Lithium is used primarily as a mood stabilizer, as it has the unique ability to treat both mania and depression. Unfortunately, the downside of lithium is that it has a very narrow therapeutic window, meaning the blood levels which provide benefits are very close to the blood levels which cause side effects and toxicity. Because of the need for such close monitoring of blood levels, the medication has largely fallen out of favor except for certain diseases like bipolar disorder.
Poor Outcomes for Older Adults with Depression
Depression creates significant physical, psychological, and social burdens for all age groups. Depression can lead to decreased daily functioning, the onset of chronic illnesses, mortality, and increased use of health care services. Older adults are not immune to depressive symptoms or its negative effects, and may have poorer outcomes than younger age groups, according to a new study published in the British Medical Journal (BMJ).
Logistical Barriers to Stem Cell Research
I recently attended a lecture by Wise Young, MD, PhD, who is a prolific researcher in the fields of spinal cord injury and stem cells. The lecture was fascinating, and part of the discussion was the current model for stem cell research. Currently we have two types of stem cells which are available for study: embryonic stem cells and induced pluripotent stem cells (iPSCs). As is well known, embryonic stem cells are derived from fertilized embryos that are allowed to multiply briefly before the cells are harvested. iPSCs are precursor cells found in adults, which are then chemically treated to revert them back to a stem cell.
Popular Posts
- The Love Drug
- Women After Sex
- Fatty Acids and Suicide Risk
- Mind Games - Science's Attempts at Thought Control
- Mental Health Disorders Prevalent Among Youth Worldwide
- Is Giftedness Nothing More than Good Genes?
- Risks of Personalized Medicine
- Behind the Masks - The Mysteries of Dissociative Identity Disorder
- The NeuroSocial Network
- Inside Your Brain on Holiday
Future Posts
Latest Posts
- Media Violence Leads to Real Violence
- Intelligence – Are You Holding Back Your Brain?
- Childhood Aggression Predicts Health Care Use Later in Life
- The Brain’s Border Patrol – Blood Brain Barrier
- Risks of Personalized Medicine
- BED-head and Obesity – Food for Thought
- Salvia Divinorum – DEA Control over Magic in the Mint
- Mighty Microglia – The Brain’s Immune Cells Key to Treating Brain Diseases
- Does Personality Play a Role in the Stress of Caregiving?
- Economic Burden of Poor Mental Health
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