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Monthly Archive for January, 2009

Colorful candy

Health & Healthcare

Fructose Leads to Leptin Resistance and Obesity

January 14, 2009 | By Jennifer Gibson, PharmD | 3 Comments

Obesity is on the rise worldwide, and poor diet and lack of regular physical activity are often cited as culprits. Residents of many industrialized nations, including the United States, have diets that are high in fat, calories, and sweeteners that lead to overweight and obesity and the related metabolic syndromes. Lately, researchers have focused attention on fructose as an identifiable offender in the obesity epidemic. A new study in rats reveals that fructose may lead to leptin resistance, which, in turn, leads to overweight and obesity.

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BioPsychoSocial Health

Stressed By His Short Allele

January 12, 2009 | By Erin Falconer, MS | 4 Comments

The serotonin (neurochemical) system in the brain has long been a target for interventions aimed at reducing depression and stress. Selective Serotonin Reuptake Inhibitors (SSRIs) are often used to balance mood and counteract high levels of anxiety. It is not surprising then that scientists are now finding that individual differences in the genetic makeup of this serotonin system may have a significant impact on one’s vulnerability to mental illness.Individual differences in the genetic makeup of the serotonin system have been shown to increase one’s vulnerability to depression, anxiety and other psychiatric conditions, particularly if individuals are exposed to stressful events in their lives.

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Drugs & Clinical Trials

Safety Concerns with Prescription Drug Samples

January 10, 2009 | By Jennifer Gibson, PharmD | No Comments

Drug manufacturers widely use prescription drug samples as a marketing tool. In 2004, drug samples accounted for approximately half of the pharmaceutical industry’s marketing budget, or $16 billion. An advantage, touted by pharmaceutical companies and some physicians, is that these samples are made available to low-income and uninsured patients, providing them with otherwise unaffordable medications. There is new evidence, however, that, not only do the samples not reduce drug costs and not go to the most disadvantaged patients, but there are also significant safety concerns with some drug samples.

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Neuroscience & Neurology

Deep Brain Stimulation for Pleasure

January 8, 2009 | By Sajid Surve, DO | 6 Comments

Scientists out of Oxford University have developed a deep brain stimulation protocol for the orbitofrontal cortex of the brain, a small center behind the eyes which is believed to have a role in our perception of pleasure associated with food and sex. Dr. Tipu Aziz, a professor of neurosurgery at Oxford remarks, "A few years ago, a scientist implanted such a device into the brain of a woman with a low sex drive and turned her into a very sexually active woman. She didn't like the sudden change, so the wiring in her head was removed." The doctor further comments that a "sex chip" utilizing this technology could be available within 10 years.

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