Comments on: Alzheimer’s Drug to Treat Binge Eating Disorder http://brainblogger.com/2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/ Topics from multidimensional biopsychosocial perspectives. Sat, 20 Mar 2010 18:24:34 +0000 http://wordpress.org/?v=2.9.2 hourly 1 By: TonyVhttp://brainblogger.com/2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/#comment-368444 TonyV Thu, 04 Dec 2008 11:50:32 +0000 http://brainblogger.com/?p=1790#comment-368444 I'm leery of any drug that promises to fix an illness that has been around for centuries. It seems to me that these drugs never pan out. What has finally worked for me is joining a 12 step program to fight my disease from the emotional/spiritual angle. I’m leery of any drug that promises to fix an illness that has been around for centuries. It seems to me that these drugs never pan out. What has finally worked for me is joining a 12 step program to fight my disease from the emotional/spiritual angle.

]]> By: The Neurocritichttp://brainblogger.com/2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/#comment-356670 The Neurocritic Wed, 19 Nov 2008 21:01:52 +0000 http://brainblogger.com/?p=1790#comment-356670 "There was no significant change in BMI, body weight, depression, or anxiety. "Doesn't seem like it was subjectively helpful to the patients, then. “There was no significant change in BMI, body weight, depression, or anxiety. ”

Doesn’t seem like it was subjectively helpful to the patients, then.

]]> By: Tiptoehttp://brainblogger.com/2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/#comment-353911 Tiptoe Mon, 17 Nov 2008 06:48:25 +0000 http://brainblogger.com/?p=1790#comment-353911 Interesting study, though definitely needs to be on a larger scale. My feeling why memantine works is due to where the drug targets in the brain. Though the Alzheimer's and BED are entirely different, it looks like memantine can help by blocking the NMDA glutamate receptors. With BED, this might be helpful in controlling the hormone leptin signaling. Interesting study, though definitely needs to be on a larger scale. My feeling why memantine works is due to where the drug targets in the brain. Though the Alzheimer’s and BED are entirely different, it looks like memantine can help by blocking the NMDA glutamate receptors. With BED, this might be helpful in controlling the hormone leptin signaling.

]]> By: Neuroskeptichttp://brainblogger.com/2008/11/10/alzheimers-drug-to-treat-binge-eating-disorder/#comment-353286 Neuroskeptic Sun, 16 Nov 2008 19:19:51 +0000 http://brainblogger.com/?p=1790#comment-353286 Hmm - that's interesting. I wonder how it works (if it does?) I'd have thought that any appetite suppressant would be effective in B.E.D - does memantine suppress appetite? It's a D2 agonist, amongst other things, so it might do.Also, I know that antidepressants reduce binge eating in bulemia, and memantine has been trialled as an antidepressant (<a href="http://ajp.psychiatryonline.org/cgi/content/full/163/1/153" rel="nofollow">although it doesn't seem to work very well.)</a> Hmm – that’s interesting. I wonder how it works (if it does?) I’d have thought that any appetite suppressant would be effective in B.E.D – does memantine suppress appetite? It’s a D2 agonist, amongst other things, so it might do.

Also, I know that antidepressants reduce binge eating in bulemia, and memantine has been trialled as an antidepressant (although it doesn’t seem to work very well.)

]]>